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10.1002/jcu.22386

http://scihub22266oqcxt.onion/10.1002/jcu.22386
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27492745!ä!27492745

suck abstract from ncbi


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pmid27492745      J+Clin+Ultrasound 2017 ; 45 (3): 168-170
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  • A multidisciplinary approach to prenatal treatment of congenital long QT syndrome #MMPMID27492745
  • Crimmins S; Vashit S; Doyle L; Harman C; Turan O; Turan S
  • J Clin Ultrasound 2017[Mar]; 45 (3): 168-170 PMID27492745show ga
  • A 27-week fetus evaluated for bradycardia and hydrops was found to have anti-SSA-negative 2 degrees atrioventricular block and ventricular tachycardia. A presumptive diagnosis of fetal long QT syndrome was made. Transplacental pharmacotherapy with intravenous magnesium and lidocaine restored sinus rhythm. At 30 6/7 weeks, the infant was delivered due to premature labor. Despite postnatal treatment with mexiletine and propranolol, she developed torsades de pointes. Ultimately, a de novo KCNH2 G628S mutation was diagnosed. She received an implantable cardiac defibrillator at 5 months of age. Early diagnosis and a multidisciplinary approach allowed successful in utero treatment and anticipatory postnatal management. (c) 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45:168-170, 2017.
  • |Adult[MESH]
  • |Electrocardiography[MESH]
  • |Female[MESH]
  • |Heart Rate Determination/methods[MESH]
  • |Humans[MESH]
  • |Lidocaine/therapeutic use[MESH]
  • |Long QT Syndrome/*diagnosis/embryology/*therapy[MESH]
  • |Magnesium/therapeutic use[MESH]
  • |Monitoring, Physiologic/methods[MESH]
  • |Pregnancy[MESH]
  • |Prenatal Diagnosis/*methods[MESH]
  • |Ultrasonography, Prenatal[MESH]


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