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10.1002/jmv.24652 http://scihub22266oqcxt.onion/10.1002/jmv.24652 27486688!7166981!27486688     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2017 ; 89 (3): 542-545 Nephropedia Template TP {{tp|p=27486688|t=2017. Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection |pdf=|usr=}}{{27486688}} gab.com Text Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=27486688 #FOAvip The spike glycoprotein of the Middle East respiratory coronavirus (MERS-CoV) facilitates receptor binding and cell entry. During investigation of a multi-facility outbreak of MERS-CoV in Taif, Saudi Arabia, we identified a mixed population of wild-type and variant sequences with a large 530 nucleotide deletion in the spike gene from the serum of one patient. The out of frame deletion predicted loss of most of the S2 subunit of the spike protein leaving the S1 subunit with an intact receptor binding domain. This finding documents human infection with a novel genetic variant of MERS-CoV present as a quasispecies. J. Med. Virol. 89:542-545, 2017. (c) 2016 Wiley Periodicals, Inc. Twit Text FOAVip Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=27486688 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27486688 #FOAvip English Wikipedia <ref>{{Cite pmid|27486688}}</ref> Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection #MMPMID27486688 Lu X; Rowe LA; Frace M; Stevens J; Abedi GR; Elnile O; Banassir T; Al-Masri M; Watson JT; Assiri A; Erdman DD J Med Virol 2017[Mar]; 89 (3): 542-545 PMID27486688show ga The spike glycoprotein of the Middle East respiratory coronavirus (MERS-CoV) facilitates receptor binding and cell entry. During investigation of a multi-facility outbreak of MERS-CoV in Taif, Saudi Arabia, we identified a mixed population of wild-type and variant sequences with a large 530 nucleotide deletion in the spike gene from the serum of one patient. The out of frame deletion predicted loss of most of the S2 subunit of the spike protein leaving the S1 subunit with an intact receptor binding domain. This finding documents human infection with a novel genetic variant of MERS-CoV present as a quasispecies. J. Med. Virol. 89:542-545, 2017. (c) 2016 Wiley Periodicals, Inc. |*Genetic Variation[MESH] |*Sequence Deletion[MESH] |Coronavirus Infections/epidemiology/*virology[MESH] |Disease Outbreaks[MESH] |Humans[MESH] |Middle East Respiratory Syndrome Coronavirus/*classification/*genetics/isolation & purification[MESH] |Saudi Arabia/epidemiology[MESH] |Serum/*virology[MESH]Spike gene deletion quasispecies in serum of patient with acute MERS-C(epmc).pdf DeepDyve Pubget Overpricing