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Advances in Pediatric Pharmacology, Therapeutics, and Toxicology #MMPMID27426903
Wang LA; Cohen-Wolkowiez M; Gonzalez D
Adv Pediatr 2016[Aug]; 63 (1): 227-54 PMID27426903show ga
In the United States, the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act continue to promote clinical trials in pediatric populations across all age ranges. In 2014 and 2015, over 70 changes were made to drug labels with updates on information regarding pediatric populations. Additionally, multiple new therapies have received first-approvals for the treatment of pediatric indications ranging form rare genetic metabolic diseases to oncology. In the European Union, there have been more than 30 new authorizations for medicines used in children and 130 approved pediatric investigation plans. Despite the progress that has been made over the last two years, much work remains to further the development of safe and effective therapies for pediatric patients.