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10.1080/17453674.2016.1196429 http://scihub22266oqcxt.onion/10.1080/17453674.2016.1196429 27321676/?report=reader!5251257!27321676     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Orthop 2017 ; 88 (1): 116-120 Nephropedia Template TP {{tp|p=27321676|t=2017. Improved prognosis in soft-tissue sarcoma of extremity and trunk wall |pdf=|usr=}}{{27321676}} gab.com Text Improved prognosis in soft-tissue sarcoma of extremity and trunk wall JO: Acta Orthop http://www.kidney.de/pget.php?&tw=1&pmid=27321676 #FOAvip Background and purpose - Soft-tissue sarcoma (STS) is rare, with challenging individualized treatment, so diagnostics and treatment should be centralized. Historical controls are sometimes used for investigation of whether new diagnostic or therapeutic tools affect patient outcome. However, as yet unknown factors may affect the outcome. We investigated prognostic factors and prognosis in 2 nationwide cohorts of patients diagnosed with a local STS during the periods 1998-2001 and 2005-2010, with special interest in finding factors lying behind possible improvement of prognosis. Patients and methods - 2 cohorts of patients with STS of the extremities or trunk diagnosed during the periods 1998-2001 and 2005-2010 were retrieved from the nationwide Finnish Cancer Registry. Detailed information was gathered from patient files. Results - Compared to first cohort, a larger proportion of patients with inadequate surgery in the second cohort received radiation therapy, and both the local control rate and the sarcoma-specific survival rate improved in the second cohort. For sarcoma-specific survival, cohort (HR =0.6, 95% CI: 0.5-0.9), age, depth, grade, and margin were significant factors in multivariate analysis. For local control, cohort (HR =0.6, 95% CI: 0.5-0.9), age, and margin were significant in multivariate analysis. Interpretation - Known prognostic factors including type of treatment did not entirely explain the secular trend of continuous improvement in prognosis in STS. This illustrates the danger of using historical controls for investigation of whether new diagnostic or therapeutic tools have an effect on patient outcome. Twit Text FOAVip Improved prognosis in soft-tissue sarcoma of extremity and trunk wall ????Acta Orthop http://www.kidney.de/pget.php?&tw=1&pmid=27321676 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27321676 #FOAvip English Wikipedia <ref>{{Cite pmid|27321676}}</ref> Improved prognosis in soft-tissue sarcoma of extremity and trunk wall #MMPMID27321676 Sampo MM; Klintrup K; Tukiainen EJ; Bohling TO; Blomqvist CP Acta Orthop 2017[Feb]; 88 (1): 116-120 PMID27321676show ga Background and purpose - Soft-tissue sarcoma (STS) is rare, with challenging individualized treatment, so diagnostics and treatment should be centralized. Historical controls are sometimes used for investigation of whether new diagnostic or therapeutic tools affect patient outcome. However, as yet unknown factors may affect the outcome. We investigated prognostic factors and prognosis in 2 nationwide cohorts of patients diagnosed with a local STS during the periods 1998-2001 and 2005-2010, with special interest in finding factors lying behind possible improvement of prognosis. Patients and methods - 2 cohorts of patients with STS of the extremities or trunk diagnosed during the periods 1998-2001 and 2005-2010 were retrieved from the nationwide Finnish Cancer Registry. Detailed information was gathered from patient files. Results - Compared to first cohort, a larger proportion of patients with inadequate surgery in the second cohort received radiation therapy, and both the local control rate and the sarcoma-specific survival rate improved in the second cohort. For sarcoma-specific survival, cohort (HR =0.6, 95% CI: 0.5-0.9), age, depth, grade, and margin were significant factors in multivariate analysis. For local control, cohort (HR =0.6, 95% CI: 0.5-0.9), age, and margin were significant in multivariate analysis. Interpretation - Known prognostic factors including type of treatment did not entirely explain the secular trend of continuous improvement in prognosis in STS. This illustrates the danger of using historical controls for investigation of whether new diagnostic or therapeutic tools have an effect on patient outcome. |*Population Surveillance[MESH] |*Registries[MESH] |Extremities[MESH] |Female[MESH] |Finland/epidemiology[MESH] |Follow-Up Studies[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Neoplasm Staging/*methods[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |Sarcoma/diagnosis/*epidemiology[MESH] |Survival Rate/trends[MESH] |Time Factors[MESH]Improved prognosis in soft-tissue sarcoma of extremity and trunk wall (epmc).pdf DeepDyve Pubget Overpricing