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10.1002/prca.201600002 http://scihub22266oqcxt.onion/10.1002/prca.201600002 27198131!7168043!27198131     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proteomics+Clin+Appl 2016 ; 10 (9-10): 922-948 Nephropedia Template TP {{tp|p=27198131|t=2016. Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display |pdf=|usr=}}{{27198131}} gab.com Text Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display JO: Proteomics Clin Appl http://www.kidney.de/pget.php?&tw=1&pmid=27198131 #FOAvip Antibodies are valuable molecules for the diagnostic and treatment of diseases caused by pathogens and toxins. Traditionally, these antibodies are generated by hybridoma technology. An alternative to hybridoma technology is the use of antibody phage display to generate recombinant antibodies. This in vitro technology circumvents the limitations of the immune system and allows-in theory-the generation of antibodies against all conceivable molecules. Phage display technology enables obtaining human antibodies from naive antibody gene libraries when either patients are not available or immunization is not ethically feasible. On the other hand, if patients or immunized/infected animals are available, it is common to construct immune phage display libraries to select in vivo affinity-matured antibodies. Because the phage packaged DNA sequence encoding the antibodies is directly available, the antibodies can be smoothly engineered according to the requirements of the final application. In this review, an overview of phage display derived recombinant antibodies against bacterial, viral, and eukaryotic pathogens as well as toxins for diagnostics and therapy is given. Twit Text FOAVip Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display ????Proteomics Clin Appl http://www.kidney.de/pget.php?&tw=1&pmid=27198131 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27198131 #FOAvip English Wikipedia <ref>{{Cite pmid|27198131}}</ref> Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display #MMPMID27198131 Kuhn P; Fuhner V; Unkauf T; Moreira GM; Frenzel A; Miethe S; Hust M Proteomics Clin Appl 2016[Oct]; 10 (9-10): 922-948 PMID27198131show ga Antibodies are valuable molecules for the diagnostic and treatment of diseases caused by pathogens and toxins. Traditionally, these antibodies are generated by hybridoma technology. An alternative to hybridoma technology is the use of antibody phage display to generate recombinant antibodies. This in vitro technology circumvents the limitations of the immune system and allows-in theory-the generation of antibodies against all conceivable molecules. Phage display technology enables obtaining human antibodies from naive antibody gene libraries when either patients are not available or immunization is not ethically feasible. On the other hand, if patients or immunized/infected animals are available, it is common to construct immune phage display libraries to select in vivo affinity-matured antibodies. Because the phage packaged DNA sequence encoding the antibodies is directly available, the antibodies can be smoothly engineered according to the requirements of the final application. In this review, an overview of phage display derived recombinant antibodies against bacterial, viral, and eukaryotic pathogens as well as toxins for diagnostics and therapy is given. |*Peptide Library[MESH] |Animals[MESH] |Antibodies/genetics/*immunology[MESH] |Genetic Engineering/*methods[MESH] |Humans[MESH] |Recombinant Proteins/genetics/*immunology[MESH]Recombinant antibodies for diagnostics and therapy against pathogens a(epmc).pdf DeepDyve Pubget Overpricing