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10.12659/ajcr.895721 http://scihub22266oqcxt.onion/10.12659/ajcr.895721 27049736/?report=reader!4824343!27049736     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Case+Rep 2016 ; 17 (ä): 219-23 Nephropedia Template TP {{tp|p=27049736|t=2016. Clostridium Perfringens Infection in a Febrile Patient with Severe Hemolytic Anemia |pdf=|usr=}}{{27049736}} gab.com Text Clostridium Perfringens Infection in a Febrile Patient with Severe Hemolytic Anemia JO: Am J Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=27049736 #FOAvip BACKGROUND: Clostridium perfringens (C. perfringens) can cause various infections, including gas gangrene, crepitant cellulitis, and fasciitis. While C. perfringens sepsis is uncommon, it is often rapidly fatal because the alpha toxin of this bacterium induces massive intravascular hemolysis by disrupting red blood cell membranes. CASE REPORT: We present the case of a male patient with diabetes who developed a fatal liver abscess with massive intravascular hemolysis and septic shock caused by toxigenic C. perfringens. The peripheral blood smear showed loss of central pallor, with numerous spherocytes. Multiplex PCR only detected expression of the cpa gene, indicating that the pathogen was C. perfringens type A. CONCLUSIONS: C. perfringens infection should be considered in a febrile patient who has severe hemolytic anemia with a very low MCV, hemolyzed blood sample, and negative Coombs test. The characteristic peripheral blood smear findings may facilitate rapid diagnosis. Twit Text FOAVip Clostridium Perfringens Infection in a Febrile Patient with Severe Hemolytic Anemia ????Am J Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=27049736 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27049736 #FOAvip English Wikipedia <ref>{{Cite pmid|27049736}}</ref> Clostridium Perfringens Infection in a Febrile Patient with Severe Hemolytic Anemia #MMPMID27049736 Hashiba M; Tomino A; Takenaka N; Hattori T; Kano H; Tsuda M; Takeyama N Am J Case Rep 2016[Apr]; 17 (ä): 219-23 PMID27049736show ga BACKGROUND: Clostridium perfringens (C. perfringens) can cause various infections, including gas gangrene, crepitant cellulitis, and fasciitis. While C. perfringens sepsis is uncommon, it is often rapidly fatal because the alpha toxin of this bacterium induces massive intravascular hemolysis by disrupting red blood cell membranes. CASE REPORT: We present the case of a male patient with diabetes who developed a fatal liver abscess with massive intravascular hemolysis and septic shock caused by toxigenic C. perfringens. The peripheral blood smear showed loss of central pallor, with numerous spherocytes. Multiplex PCR only detected expression of the cpa gene, indicating that the pathogen was C. perfringens type A. CONCLUSIONS: C. perfringens infection should be considered in a febrile patient who has severe hemolytic anemia with a very low MCV, hemolyzed blood sample, and negative Coombs test. The characteristic peripheral blood smear findings may facilitate rapid diagnosis. |Aged, 80 and over[MESH] |Anemia, Hemolytic/*microbiology[MESH] |Clostridium Infections/*complications/diagnosis[MESH] |Clostridium perfringens[MESH] |Fatal Outcome[MESH] |Fever/*microbiology[MESH] |Humans[MESH] |Liver Abscess/microbiology[MESH] |Male[MESH]Clostridium Perfringens Infection in a Febrile Patient with Severe Hem(epmc).pdf DeepDyve Pubget Overpricing