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10.1111/j.1601-5215.2006.00118.x

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26989971!ä!26989971

suck abstract from ncbi


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pmid26989971      Acta+Neuropsychiatr 2006 ; 18 (3-4): 177-80
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  • No borna disease virus-specific RNA detected in blood of race horses and jockeys #MMPMID26989971
  • Kim YK; Noh KB; Han CS; Moon JY; Yoon DK; Song KJ; Kim DJ; Kubera M; Maes M; Song JW
  • Acta Neuropsychiatr 2006[Jun]; 18 (3-4): 177-80 PMID26989971show ga
  • BACKGROUND: Borna disease virus (BDV) predominantly infects horses and sheep, causing a broad range of behavioural disorders. It is controversial whether BDV infects humans and causes psychiatric disorders. OBJECTIVES: We searched for BDV-derived nucleic acids in blood of race horses and jockeys riding the horses. METHODS: We assayed for the BDV genome in RNA extracted from peripheral blood mononuclear cells (PBMC) of 39 race horses and 48 jockeys. Two polymerase chain reaction protocols [one-tube reverse transcription-polymerase chain reaction (RT-PCR) and two-step RT-PCR] were used to assay BDV p24 and p40 transcripts. RESULTS: The p24 and p40 viral nucleic acid sequences were not detected in the PBMC RNAs from any of the race horses or jockeys. CONCLUSIONS: These data do not support an epidemiological association between BDV infection, race horses and humans.
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