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10.1684/mrh.2015.0395 http://scihub22266oqcxt.onion/10.1684/mrh.2015.0395 26878253!ä!26878253 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26878253&cmd=llinks): Failed to open stream: HTTP request failed! 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An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor |pdf=|usr=}}{{26878253}} gab.com Text An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor JO: Magnes Res http://www.kidney.de/pget.php?&tw=1&pmid=26878253 #FOAvip PURPOSE: Magnesium is an important electrolyte for very many cell functions and its deficiency may lead to a wide spectrum of diseases. We report a clinical case of hypomagnesemia resulting from the chronic use of a proton pump inhibitor (PPI). PPIs are drugs widely used in medical practice, and a growing number of cases of PPIs causing hypomagnesemia have been described. Our aim was to monitor the clinical and electrolyte findings during recovery from hypomagnesemia caused by long-term PPI use. RESULTS: A 65-year old female who had been using omeprazole for 10 years, presented with arrhythmia and paresthesia of the lower and upper limbs that had been attributed to severe hypomagnesemia, hypocalcemia, and hypoparathyroidism. Her laboratory tests revealed the following results: magnesium 0.6 mg/dL (NR: 1.5 to 2.5 mg/dL), calcium 7.3 mg/dL (NR: 8.5 to 10.2 mg/dL), parathyroid hormone (PTH) 13.3 pg/mL (NR: 15 to 65 pg/mL), and low urinary calcium and magnesium excretion. Her electrocardiogram disclosed typical, prolonged QT interval, ST depression, and U waves. We discuss the differential diagnoses, pathophysiology, and reversibility of symptoms after effective treatment of the hypomagnesemia. CONCLUSION: this report emphasizes that even if long-term PPI users appear largely asymptomatic, life-threatening arrhythmias can present very suddenly. Long-term PPI users should be monitored for otherwise unexplained hypomagnesemia, hypocalcemia, functional hypoparathyroidism and associated symptoms. Twit Text FOAVip An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor ????Magnes Res http://www.kidney.de/pget.php?&tw=1&pmid=26878253 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26878253 #FOAvip English Wikipedia <ref>{{Cite pmid|26878253}}</ref> An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor #MMPMID26878253 dos Santos LM; Guerra RA; Lazaretti-Castro M; Vieira JG; Portes Ede S; Dias-da-Silva MR Magnes Res 2015[Dec]; 28 (4): 136-45 PMID26878253show ga PURPOSE: Magnesium is an important electrolyte for very many cell functions and its deficiency may lead to a wide spectrum of diseases. We report a clinical case of hypomagnesemia resulting from the chronic use of a proton pump inhibitor (PPI). PPIs are drugs widely used in medical practice, and a growing number of cases of PPIs causing hypomagnesemia have been described. Our aim was to monitor the clinical and electrolyte findings during recovery from hypomagnesemia caused by long-term PPI use. RESULTS: A 65-year old female who had been using omeprazole for 10 years, presented with arrhythmia and paresthesia of the lower and upper limbs that had been attributed to severe hypomagnesemia, hypocalcemia, and hypoparathyroidism. Her laboratory tests revealed the following results: magnesium 0.6 mg/dL (NR: 1.5 to 2.5 mg/dL), calcium 7.3 mg/dL (NR: 8.5 to 10.2 mg/dL), parathyroid hormone (PTH) 13.3 pg/mL (NR: 15 to 65 pg/mL), and low urinary calcium and magnesium excretion. Her electrocardiogram disclosed typical, prolonged QT interval, ST depression, and U waves. We discuss the differential diagnoses, pathophysiology, and reversibility of symptoms after effective treatment of the hypomagnesemia. CONCLUSION: this report emphasizes that even if long-term PPI users appear largely asymptomatic, life-threatening arrhythmias can present very suddenly. Long-term PPI users should be monitored for otherwise unexplained hypomagnesemia, hypocalcemia, functional hypoparathyroidism and associated symptoms. |Aged[MESH] |Arrhythmias, Cardiac/blood/chemically induced[MESH] |Biomarkers/blood[MESH] |Diagnosis, Differential[MESH] |Down-Regulation[MESH] |Electrocardiography[MESH] |Female[MESH] |Humans[MESH] |Hypocalcemia/blood/chemically induced[MESH] |Hypoparathyroidism/blood/chemically induced[MESH] |Magnesium/*blood[MESH] |Metabolic Diseases/blood/*chemically induced/diagnosis/therapy[MESH] |Omeprazole/*adverse effects[MESH] |Paresthesia/blood/chemically induced[MESH] |Predictive Value of Tests[MESH] |Proton Pump Inhibitors/*adverse effects[MESH] |Risk Factors[MESH]An approach to the diagnosis and management of a case presenting with (epmc).pdf DeepDyve Pubget Overpricing