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10.1161/JAHA.115.002707 http://scihub22266oqcxt.onion/10.1161/JAHA.115.002707 26802105!4859391!26802105     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Heart+Assoc 2016 ; 5 (1): ä Nephropedia Template TP {{tp|p=26802105|t=2016. Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death |pdf=|usr=}}{{26802105}} gab.com Text Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death JO: J Am Heart Assoc http://www.kidney.de/pget.php?&tw=1&pmid=26802105 #FOAvip BACKGROUND: Low serum magnesium has been implicated in cardiovascular mortality, but results are conflicting and the pathway is unclear. We studied the association of serum magnesium with coronary heart disease (CHD) mortality and sudden cardiac death (SCD) within the prospective population-based Rotterdam Study, with adjudicated end points and long-term follow-up. METHODS AND RESULTS: Nine-thousand eight-hundred and twenty participants (mean age 65.1 years, 56.8% female) were included with a median follow-up of 8.7 years. We used multivariable Cox proportional hazard models and found that a 0.1 mmol/L increase in serum magnesium level was associated with a lower risk for CHD mortality (hazard ratio: 0.82, 95% CI 0.70-0.96). Furthermore, we divided serum magnesium in quartiles, with the second and third quartile combined as reference group (0.81-0.88 mmol/L). Low serum magnesium (</=0.80 mmol/L) was associated with an increased risk of CHD mortality (N=431, hazard ratio: 1.36, 95% CI 1.09-1.69) and SCD (N=217, hazard ratio: 1.54, 95% CI 1.12-2.11). Low serum magnesium was associated with accelerated subclinical atherosclerosis (expressed as increased carotid intima-media thickness: +0.013 mm, 95% CI 0.005-0.020) and increased QT-interval, mainly through an effect on heart rate (RR-interval: -7.1 ms, 95% CI -13.5 to -0.8). Additional adjustments for carotid intima-media thickness and heart rate did not change the associations with CHD mortality and SCD. CONCLUSIONS: Low serum magnesium is associated with an increased risk of CHD mortality and SCD. Although low magnesium was associated with both carotid intima-media thickness and heart rate, this did not explain the relationship between serum magnesium and CHD mortality or SCD. Future studies should focus on why magnesium associates with CHD mortality and SCD and whether intervention reduces these risks. Twit Text FOAVip Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death ????J Am Heart Assoc http://www.kidney.de/pget.php?&tw=1&pmid=26802105 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26802105 #FOAvip English Wikipedia <ref>{{Cite pmid|26802105}}</ref> Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death #MMPMID26802105 Kieboom BC; Niemeijer MN; Leening MJ; van den Berg ME; Franco OH; Deckers JW; Hofman A; Zietse R; Stricker BH; Hoorn EJ J Am Heart Assoc 2016[Jan]; 5 (1): ä PMID26802105show ga BACKGROUND: Low serum magnesium has been implicated in cardiovascular mortality, but results are conflicting and the pathway is unclear. We studied the association of serum magnesium with coronary heart disease (CHD) mortality and sudden cardiac death (SCD) within the prospective population-based Rotterdam Study, with adjudicated end points and long-term follow-up. METHODS AND RESULTS: Nine-thousand eight-hundred and twenty participants (mean age 65.1 years, 56.8% female) were included with a median follow-up of 8.7 years. We used multivariable Cox proportional hazard models and found that a 0.1 mmol/L increase in serum magnesium level was associated with a lower risk for CHD mortality (hazard ratio: 0.82, 95% CI 0.70-0.96). Furthermore, we divided serum magnesium in quartiles, with the second and third quartile combined as reference group (0.81-0.88 mmol/L). Low serum magnesium ( |Aged[MESH] |Arrhythmias, Cardiac/diagnosis/mortality[MESH] |Biomarkers/blood[MESH] |Carotid Artery Diseases/diagnosis/mortality[MESH] |Carotid Intima-Media Thickness[MESH] |Cause of Death[MESH] |Coronary Disease/*blood/diagnosis/*mortality[MESH] |Death, Sudden, Cardiac/*epidemiology[MESH] |Down-Regulation[MESH] |Electrocardiography[MESH] |Female[MESH] |Heart Rate[MESH] |Humans[MESH] |Linear Models[MESH] |Magnesium Deficiency/*blood/diagnosis/*mortality[MESH] |Magnesium/*blood[MESH] |Male[MESH] |Middle Aged[MESH] |Multivariate Analysis[MESH] |Netherlands/epidemiology[MESH] |Proportional Hazards Models[MESH] |Prospective Studies[MESH] |Risk Assessment[MESH] |Risk Factors[MESH]Serum Magnesium and the Risk of Death From Coronary Heart Disease and (epmc).pdf DeepDyve Pubget Overpricing