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10.1038/jp.2015.217

http://scihub22266oqcxt.onion/10.1038/jp.2015.217
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26796125!ä!26796125

suck abstract from ncbi


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pmid26796125      J+Perinatol 2016 ; 36 (6): 474-80
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  • The spectrum of onset of acute kidney injury in premature infants less than 30 weeks gestation #MMPMID26796125
  • Weintraub AS; Connors J; Carey A; Blanco V; Green RS
  • J Perinatol 2016[Jun]; 36 (6): 474-80 PMID26796125show ga
  • OBJECTIVE: To determine risk factors for acute kidney injury (AKI) in preterm infants as a function of time of onset. STUDY DESIGN: In this 5 1/2-year, single-center, retrospective study, incidence and timing of AKI was determined using modified Acute Kidney Injury Network criteria. Characteristics of newborns with and without AKI were compared by chi square and t-tests. Logistic regression was used to examine risk factors for AKI as a function of time of onset and potential confounders. RESULT: AKI occurred in 30.3% of 357 neonates; 72.2% was stage 1. Gestational ages (GA), initial Cr, maternal magnesium and volume resuscitation were associated with early AKI (days 0 to 1). Volume resuscitation, umbilical arterial line and receipt of non-steroidal anti-inflammatory drug (NSAID) for patent ductus arteriosus were associated with intermediate AKI (days 2 to 5). GA, steroids for early hypotension, necrotizing enterocolitis and sepsis were associated with late AKI (?day 6). CONCLUSION: Stage 1 AKI is a common morbidity in our population. Risk factors for AKI in our population differed with time of onset.
  • |*Acute Kidney Injury/diagnosis/epidemiology/etiology/prevention & control[MESH]
  • |*Ductus Arteriosus, Patent/drug therapy/epidemiology[MESH]
  • |*Sepsis/epidemiology/therapy[MESH]
  • |Age of Onset[MESH]
  • |Anti-Inflammatory Agents, Non-Steroidal/therapeutic use[MESH]
  • |Enterocolitis, Necrotizing/*epidemiology[MESH]
  • |Female[MESH]
  • |Fluid Therapy/adverse effects[MESH]
  • |Gestational Age[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Infant, Newborn[MESH]
  • |Infant, Premature, Diseases/epidemiology[MESH]
  • |Infant, Very Low Birth Weight[MESH]
  • |Male[MESH]
  • |Patient Acuity[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |Statistics as Topic[MESH]


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