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10.1038/srep17226 http://scihub22266oqcxt.onion/10.1038/srep17226 26611279!4661702!26611279     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): 17226 Nephropedia Template TP {{tp|p=26611279|t=2015. Bones hold the key to DNA virus history and epidemiology |pdf=|usr=}}{{26611279}} gab.com Text Bones hold the key to DNA virus history and epidemiology JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26611279 #FOAvip DNA in human skeletal remains represents an important historical source of host genomic information and potentially of infecting viruses. However, little is known about viral persistence in bone. We searched ca. 70-year-old long bones of putative Finnish casualties from World War II for parvovirus B19 (B19V) DNA, and found a remarkable prevalence of 45%. The viral sequences were exclusively of genotypes 2 (n = 41), which disappeared from circulation in 1970 s, or genotype 3 (n = 2), which has never been reported in Northern Europe. Based on mitochondrial and Y-chromosome profiling, the two individuals carrying B19V genotype 3 were likely from the Soviet Red Army. The most recent common ancestor for all genotypes was estimated at early 1800s. This work demonstrates the forms of B19V that circulated in the first half of the 20(th) century and provides the first evidence of the suitability of bone for exploration of DNA viruses. Twit Text FOAVip Bones hold the key to DNA virus history and epidemiology ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26611279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26611279 #FOAvip English Wikipedia <ref>{{Cite pmid|26611279}}</ref> Bones hold the key to DNA virus history and epidemiology #MMPMID26611279 Toppinen M; Perdomo MF; Palo JU; Simmonds P; Lycett SJ; Soderlund-Venermo M; Sajantila A; Hedman K Sci Rep 2015[Nov]; 5 (ä): 17226 PMID26611279show ga DNA in human skeletal remains represents an important historical source of host genomic information and potentially of infecting viruses. However, little is known about viral persistence in bone. We searched ca. 70-year-old long bones of putative Finnish casualties from World War II for parvovirus B19 (B19V) DNA, and found a remarkable prevalence of 45%. The viral sequences were exclusively of genotypes 2 (n = 41), which disappeared from circulation in 1970 s, or genotype 3 (n = 2), which has never been reported in Northern Europe. Based on mitochondrial and Y-chromosome profiling, the two individuals carrying B19V genotype 3 were likely from the Soviet Red Army. The most recent common ancestor for all genotypes was estimated at early 1800s. This work demonstrates the forms of B19V that circulated in the first half of the 20(th) century and provides the first evidence of the suitability of bone for exploration of DNA viruses. |*Genotype[MESH] |*Phylogeny[MESH] |Bone and Bones/*virology[MESH] |Cadaver[MESH] |DNA, Viral/*genetics[MESH] |Europe/epidemiology[MESH] |Exhumation[MESH] |History, 20th Century[MESH] |Humans[MESH] |Military Personnel/history[MESH] |Parvoviridae Infections/*epidemiology/virology[MESH] |Parvovirus B19, Human/classification/*genetics/isolation & purification[MESH] |Prevalence[MESH] |Real-Time Polymerase Chain Reaction[MESH] |USSR/epidemiology[MESH]Bones hold the key to DNA virus history and epidemiology (epmc).pdf DeepDyve Pubget Overpricing