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10.1016/j.apsb.2014.06.012 http://scihub22266oqcxt.onion/10.1016/j.apsb.2014.06.012 26579393/?report=reader!4629089!26579393     free     free     free       Acta+Pharm+Sin+B 2014 ; 4 (4): 258-65 Nephropedia Template TP {{tp|p=26579393|t=2014. Antibiotic drugs targeting bacterial RNAs |pdf=|usr=}}{{26579393}} gab.com Text Antibiotic drugs targeting bacterial RNAs JO: Acta Pharm Sin B http://www.kidney.de/pget.php?&tw=1&pmid=26579393 #FOAvip RNAs have diverse structures that include bulges and internal loops able to form tertiary contacts or serve as ligand binding sites. The recent increase in structural and functional information related to RNAs has put them in the limelight as a drug target for small molecule therapy. In addition, the recognition of the marked difference between prokaryotic and eukaryotic rRNA has led to the development of antibiotics that specifically target bacterial rRNA, reduce protein translation and thereby inhibit bacterial growth. To facilitate the development of new antibiotics targeting RNA, we here review the literature concerning such antibiotics, mRNA, riboswitch and tRNA and the key methodologies used for their screening. Twit Text FOAVip Antibiotic drugs targeting bacterial RNAs ????Acta Pharm Sin B http://www.kidney.de/pget.php?&tw=1&pmid=26579393 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26579393 #FOAvip English Wikipedia <ref>{{Cite pmid|26579393}}</ref> Antibiotic drugs targeting bacterial RNAs #MMPMID26579393 Hong W; Zeng J; Xie J Acta Pharm Sin B 2014[Aug]; 4 (4): 258-65 PMID26579393show ga RNAs have diverse structures that include bulges and internal loops able to form tertiary contacts or serve as ligand binding sites. The recent increase in structural and functional information related to RNAs has put them in the limelight as a drug target for small molecule therapy. In addition, the recognition of the marked difference between prokaryotic and eukaryotic rRNA has led to the development of antibiotics that specifically target bacterial rRNA, reduce protein translation and thereby inhibit bacterial growth. To facilitate the development of new antibiotics targeting RNA, we here review the literature concerning such antibiotics, mRNA, riboswitch and tRNA and the key methodologies used for their screening. äAntibiotic drugs targeting bacterial RNAs (epmc).pdf DeepDyve Pubget Overpricing