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10.1002/jmv.24411

http://scihub22266oqcxt.onion/10.1002/jmv.24411
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26488078!7166970!26488078
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suck abstract from ncbi


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pmid26488078      J+Med+Virol 2016 ; 88 (5): 774-81
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  • Circulation of human metapneumovirus among children with influenza-like illness in Wuhan, China #MMPMID26488078
  • Kong W; Wang Y; Zhu H; Lin X; Yu B; Hu Q; Yang X; Guo D; Peng J; Zhou D
  • J Med Virol 2016[May]; 88 (5): 774-81 PMID26488078show ga
  • Human metapneumovirus (HMPV) is a worldwide distributed pathogen of the respiratory tract. The objectives of this study were to identify HMPV infections among children with influenza-like illness (ILI) in Wuhan and to assess circulation patterns and molecular diversity of HMPV in this area. From July 2008 to December 2013, a total of 3,883 throat swab samples were collected from ILI outpatients under 16 years old. HMPV RNA was detected in 171 samples (4.40%). All the four subtypes of HMPV were identified, among which A2 was the most common subtype (61/145, 42.1%), followed by B1, B2, and A1. During the study period, HMPV circulation presented a biennial alternation between high and low incidence in Wuhan and the seasonal peak also shift between winter and spring in two continuous seasons. Subtype A2, B1, and B2 co-circulated during the study period, with genotype A prevailing in epidemic season 2008-2009 and 2012-2013, and genotype B prevailing during other periods. This large-scale analysis of HMPV prevalence in ILI outpatient children improves the understanding of local HMPV circulation patterns and provides molecular epidemic evidence for comparative analysis of HMPV infection.
  • |*Genetic Variation[MESH]
  • |*Genotype[MESH]
  • |Adolescent[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |China/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Influenza, Human/*pathology[MESH]
  • |Male[MESH]
  • |Metapneumovirus/*classification/genetics/*isolation & purification[MESH]
  • |Molecular Epidemiology[MESH]
  • |Outpatients[MESH]
  • |Paramyxoviridae Infections/*epidemiology/*pathology/virology[MESH]
  • |Pharynx/virology[MESH]
  • |RNA, Viral/analysis[MESH]


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