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10.1111/adb.12314

http://scihub22266oqcxt.onion/10.1111/adb.12314
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suck abstract from ncbi


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pmid26435524      Addict+Biol 2016 ; 21 (1): 3-22
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  • Neural substrates of cue reactivity: association with treatment outcomes and relapse #MMPMID26435524
  • Courtney KE; Schacht JP; Hutchison K; Roche DJ; Ray LA
  • Addict Biol 2016[Jan]; 21 (1): 3-22 PMID26435524show ga
  • Given the strong evidence for neurological alterations at the basis of drug dependence, functional magnetic resonance imaging (fMRI) represents an important tool in the clinical neuroscience of addiction. fMRI cue-reactivity paradigms represent an ideal platform to probe the involvement of neurobiological pathways subserving the reward/motivation system in addiction and potentially offer a translational mechanism by which interventions and behavioral predictions can be tested. Thus, this review summarizes the research that has applied fMRI cue-reactivity paradigms to the study of adult substance use disorder treatment responses. Studies utilizing fMRI cue-reactivity paradigms for the prediction of relapse and as a means to investigate psychosocial and pharmacological treatment effects on cue-elicited brain activation are presented within four primary categories of substances: alcohol, nicotine, cocaine and opioids. Lastly, suggestions for how to leverage fMRI technology to advance addiction science and treatment development are provided.
  • |*Cues[MESH]
  • |Alcoholism/*physiopathology/therapy[MESH]
  • |Brain/*physiopathology[MESH]
  • |Cocaine-Related Disorders/*physiopathology/therapy[MESH]
  • |Functional Neuroimaging[MESH]
  • |Humans[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Opioid-Related Disorders/*physiopathology/therapy[MESH]
  • |Prognosis[MESH]
  • |Recurrence[MESH]
  • |Tobacco Use Disorder/*physiopathology/therapy[MESH]
  • |Translational Research, Biomedical[MESH]


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