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10.1016/0002-9149(89)90936-3 http://scihub22266oqcxt.onion/10.1016/0002-9149(89)90936-3 2643290!ä!2643290 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Cardiol 1989 ; 63 (4): 32B-36B Nephropedia Template TP {{tp|p=2643290|t=1989. Efficacy and safety of triamterene/hydrochlorothiazide combinations in mild systemic hypertension |pdf=|usr=}}{{2643290}} gab.com Text Efficacy and safety of triamterene/hydrochlorothiazide combinations in mild systemic hypertension JO: Am J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=2643290 #FOAvip After a 3-week placebo lead-in (Period 1), 78 patients with sitting diastolic blood pressures (BPs) of greater than or equal to 90 and less than or equal to 105 mm Hg entered a 4-week period (Period 2) during which they received triamterene (TMT) 37.5 mg/hydrochlorothiazide (HCTZ) 25 mg/day. Four weeks of therapy with TMT 37.5 mg/HCTZ 25 mg resulted in a statistically significant decrease in mean BP of -15.0/-9.6 mm Hg. Mean BP changed from 145/95 to 130/85 mm Hg. Fifty-nine percent of patients were classified as responders as defined by study criteria. An additional 4 weeks of therapy (Period 3) for responders produced no further change in BP. Nonresponders as a group continued to have a further decrease in BP in Period 3. However, only patients in whom therapy was transferred to TMT 75 mg/HCTZ 50 mg had a statistically significant decrease. All patients who changed to the higher dose combination achieved goal BP by the end of the study. Of the nonresponders who continued to take TMT 37.5 mg/HCTZ 25 mg, 69% achieved goal diastolic BP by the end of Period 3. Three patients were withdrawn because of adverse experiences, 1 of which was considered treatment related. Of 58 reports of adverse experiences, 8 were considered possibly related and 2 probably related to therapy. There was a total of 8 clinically significant abnormal laboratory values, 1 of which was considered to have a possible relation to therapy. Twit Text FOAVip Efficacy and safety of triamterene/hydrochlorothiazide combinations in mild systemic hypertension ????Am J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=2643290 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2643290 #FOAvip English Wikipedia <ref>{{Cite pmid|2643290}}</ref> Efficacy and safety of triamterene/hydrochlorothiazide combinations in mild systemic hypertension #MMPMID2643290 Schnaper HW; Maxwell MH Am J Cardiol 1989[Jan]; 63 (4): 32B-36B PMID2643290show ga After a 3-week placebo lead-in (Period 1), 78 patients with sitting diastolic blood pressures (BPs) of greater than or equal to 90 and less than or equal to 105 mm Hg entered a 4-week period (Period 2) during which they received triamterene (TMT) 37.5 mg/hydrochlorothiazide (HCTZ) 25 mg/day. Four weeks of therapy with TMT 37.5 mg/HCTZ 25 mg resulted in a statistically significant decrease in mean BP of -15.0/-9.6 mm Hg. Mean BP changed from 145/95 to 130/85 mm Hg. Fifty-nine percent of patients were classified as responders as defined by study criteria. An additional 4 weeks of therapy (Period 3) for responders produced no further change in BP. Nonresponders as a group continued to have a further decrease in BP in Period 3. However, only patients in whom therapy was transferred to TMT 75 mg/HCTZ 50 mg had a statistically significant decrease. All patients who changed to the higher dose combination achieved goal BP by the end of the study. Of the nonresponders who continued to take TMT 37.5 mg/HCTZ 25 mg, 69% achieved goal diastolic BP by the end of Period 3. Three patients were withdrawn because of adverse experiences, 1 of which was considered treatment related. Of 58 reports of adverse experiences, 8 were considered possibly related and 2 probably related to therapy. There was a total of 8 clinically significant abnormal laboratory values, 1 of which was considered to have a possible relation to therapy. |Antihypertensive Agents/adverse effects/*therapeutic use[MESH] |Blood Pressure/drug effects[MESH] |Clinical Trials as Topic[MESH] |Double-Blind Method[MESH] |Drug Combinations/adverse effects/therapeutic use[MESH] |Humans[MESH] |Hydrochlorothiazide/adverse effects/*therapeutic use[MESH] |Hypertension/*drug therapy[MESH] |Magnesium/blood[MESH] |Potassium/blood[MESH] |Random Allocation[MESH]Efficacy and safety of triamterene/hydrochlorothiazide combinations in(epmc).pdf DeepDyve Pubget Overpricing