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10.1080/2162402X.2015.1022308

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1022308
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26405580!4570111!26405580
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suck abstract from ncbi

pmid26405580      Oncoimmunology 2015 ; 4 (8): e1022308
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  • Fbxw7 suppresses cancer metastasis by inhibiting niche formation #MMPMID26405580
  • Yumimoto K; Nakayama KI
  • Oncoimmunology 2015[Aug]; 4 (8): e1022308 PMID26405580show ga
  • Fbxw7 has been identified as an oncosuppressor protein in many types of cancer. We have recently shown that loss of Fbxw7 in bone marrow-derived stromal cells (BMSCs) promotes cancer metastasis by increasing production of the chemokine CCL2, which attracts monocytic myeloid-derived suppressor cells (Mo-MDSCs) and macrophages to the metastatic niche.
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