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10.1177/2040622315590757 http://scihub22266oqcxt.onion/10.1177/2040622315590757 26336595!4549695!26336595     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ther+Adv+Chronic+Dis 2015 ; 6 (5): 264-72 Nephropedia Template TP {{tp|p=26336595|t=2015. Medical treatment update on pulmonary arterial hypertension |pdf=|usr=}}{{26336595}} gab.com Text Medical treatment update on pulmonary arterial hypertension JO: Ther Adv Chronic Dis http://www.kidney.de/pget.php?&tw=1&pmid=26336595 #FOAvip Pulmonary arterial hypertension is a chronic, progressive disease of the pulmonary vasculature resulting in poor outcomes if left untreated. The management of group 1 pulmonary arterial hypertension has included the use of prostanoids, phosphodiesterase-5 inhibitors, and endothelin receptor antagonists targeting the prostacyclin, endothelin-1, and nitric oxide pathways. Three new medications have been approved by the US Food and Drug Administration over the past couple of years. Macitentan is the newest endothelin receptor antagonist, riociguat is a soluble guanylate cyclase stimulator, and treprostinil diolamine is the first oral prostanoid. This review will focus on the key trials leading to their approval, special considerations for each medication, and their potential place in therapy. The use of combination therapy as initial therapy in pulmonary arterial hypertension will also be discussed. Twit Text FOAVip Medical treatment update on pulmonary arterial hypertension ????Ther Adv Chronic Dis http://www.kidney.de/pget.php?&tw=1&pmid=26336595 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26336595 #FOAvip English Wikipedia <ref>{{Cite pmid|26336595}}</ref> Medical treatment update on pulmonary arterial hypertension #MMPMID26336595 Enderby CY; Burger C Ther Adv Chronic Dis 2015[Sep]; 6 (5): 264-72 PMID26336595show ga Pulmonary arterial hypertension is a chronic, progressive disease of the pulmonary vasculature resulting in poor outcomes if left untreated. The management of group 1 pulmonary arterial hypertension has included the use of prostanoids, phosphodiesterase-5 inhibitors, and endothelin receptor antagonists targeting the prostacyclin, endothelin-1, and nitric oxide pathways. Three new medications have been approved by the US Food and Drug Administration over the past couple of years. Macitentan is the newest endothelin receptor antagonist, riociguat is a soluble guanylate cyclase stimulator, and treprostinil diolamine is the first oral prostanoid. This review will focus on the key trials leading to their approval, special considerations for each medication, and their potential place in therapy. The use of combination therapy as initial therapy in pulmonary arterial hypertension will also be discussed. äMedical treatment update on pulmonary arterial hypertension (epmc).pdf DeepDyve Pubget Overpricing