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http://scihub22266oqcxt.onion/ 26279747!4532736!26279747     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transl+Res 2015 ; 7 (6): 1021-31 Nephropedia Template TP {{tp|p=26279747|t=2015. Angiotensin II in atrial structural remodeling: the role of Ang II/JAK/STAT3 signaling pathway |pdf=|usr=}}{{26279747}} gab.com Text Angiotensin II in atrial structural remodeling: the role of Ang II/JAK/STAT3 signaling pathway JO: Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26279747 #FOAvip Ang II/JAK/STAT3 signaling pathway is known to be involved in atrial remodeling associated with development and progression of atrial fibrillation. In the present study, we used in vivo animal model and human atrial specimens to further characterize the role of this pathway in the atrial structural remodeling. We observed an elevated level of Ang II in the atrial samples of AF patients. This increase in Ang II was accompanied by increased expression of collagens I and III, MMP1, MMP2 and elevated phosphorylation of STAT3. Using rat models, we demonstrated that Ang II infusion induced profound changes in the level of apoptosis, expression of collagen subtypes I and III, caspase-3, caspase-8, MMP1, MMP2 and redistribution of cytochrome C. The data further support the key role of Ang II in the development of AF and highlight the specific mechanisms and changes associated with this process. Twit Text FOAVip Angiotensin II in atrial structural remodeling: the role of Ang II/JAK/STAT3 signaling pathway ????Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26279747 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26279747 #FOAvip English Wikipedia <ref>{{Cite pmid|26279747}}</ref> Angiotensin II in atrial structural remodeling: the role of Ang II/JAK/STAT3 signaling pathway #MMPMID26279747 Zheng L; Jia X; Zhang C; Wang D; Cao Z; Wang J; Du X Am J Transl Res 2015[]; 7 (6): 1021-31 PMID26279747show ga Ang II/JAK/STAT3 signaling pathway is known to be involved in atrial remodeling associated with development and progression of atrial fibrillation. In the present study, we used in vivo animal model and human atrial specimens to further characterize the role of this pathway in the atrial structural remodeling. We observed an elevated level of Ang II in the atrial samples of AF patients. This increase in Ang II was accompanied by increased expression of collagens I and III, MMP1, MMP2 and elevated phosphorylation of STAT3. Using rat models, we demonstrated that Ang II infusion induced profound changes in the level of apoptosis, expression of collagen subtypes I and III, caspase-3, caspase-8, MMP1, MMP2 and redistribution of cytochrome C. The data further support the key role of Ang II in the development of AF and highlight the specific mechanisms and changes associated with this process. äAngiotensin II in atrial structural remodeling: the role of Ang II/JAK(epmc).pdf DeepDyve Pubget Overpricing