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10.1186/s40035-015-0031-3 http://scihub22266oqcxt.onion/10.1186/s40035-015-0031-3 26029363!4449961!26029363     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26029363&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Transl+Neurodegener 2015 ; 4 (?): 10 Nephropedia Template TP {{tp|p=26029363|t=2015. Acid-sensing ion channels: potential therapeutic targets for neurologic diseases |pdf=|usr=}}{{26029363}} gab.com Text Acid-sensing ion channels: potential therapeutic targets for neurologic diseases JO: Transl Neurodegener http://www.kidney.de/pget.php?&tw=1&pmid=26029363 #FOAvip Maintaining the physiological pH of interstitial fluid is crucial for normal cellular functions. In disease states, tissue acidosis is a common pathologic change causing abnormal activation of acid-sensing ion channels (ASICs), which according to cumulative evidence, significantly contributes to inflammation, mitochondrial dysfunction, and other pathologic mechanisms (i.e., pain, stroke, and psychiatric conditions). Thus, it has become increasingly clear that ASICs are critical in the progression of neurologic diseases. This review is focused on the importance of ASICs as potential therapeutic targets in combating neurologic diseases. Twit Text FOAVip Acid-sensing ion channels: potential therapeutic targets for neurologic diseases ????Transl Neurodegener http://www.kidney.de/pget.php?&tw=1&pmid=26029363 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26029363 #FOAvip English Wikipedia <ref>{{Cite pmid|26029363}}</ref> Acid-sensing ion channels: potential therapeutic targets for neurologic diseases #MMPMID26029363 Liu S; Cheng XY; Wang F; Liu CF Transl Neurodegener 2015[]; 4 (?): 10 PMID26029363show ga Maintaining the physiological pH of interstitial fluid is crucial for normal cellular functions. In disease states, tissue acidosis is a common pathologic change causing abnormal activation of acid-sensing ion channels (ASICs), which according to cumulative evidence, significantly contributes to inflammation, mitochondrial dysfunction, and other pathologic mechanisms (i.e., pain, stroke, and psychiatric conditions). Thus, it has become increasingly clear that ASICs are critical in the progression of neurologic diseases. This review is focused on the importance of ASICs as potential therapeutic targets in combating neurologic diseases. ?Acid-sensing ion channels: potential therapeutic targets for neurologi(epmc).pdf DeepDyve Pubget Overpricing