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10.1093/ndtplus/sfq076

http://scihub22266oqcxt.onion/10.1093/ndtplus/sfq076
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25949430!4421504!25949430
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suck abstract from ncbi

pmid25949430      NDT+Plus 2010 ; 3 (4): 357-9
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  • Steroid-responsive nephrotic syndrome in a patient with proliferative glomerulonephritis with monoclonal IgG deposits with pure mesangial proliferative features #MMPMID25949430
  • Komatsuda A; Wakui H; Ohtani H; Nimura T; Sawada K
  • NDT Plus 2010[Aug]; 3 (4): 357-9 PMID25949430show ga
  • A 78-year-old woman developed acute-onset nephrotic syndrome. A renal biopsy showed mild mesangial proliferative glomerulonephritis. Immunofluorescence studies revealed granular IgG3- lambda deposits within the mesangial area and along the glomerular capillary walls. Electron microscopy showed mesangial and subendothelial granular electron-dense deposits. The pattern of deposition was predominantly mesangial. Serum or urine monoclonal proteins were not detected. Middle-dose steroid therapy induced a rapid remission of nephrotic syndrome. We consider that this is the first case of steroid-responsive nephrotic syndrome due to an extremely rare glomerular disease, proliferative glomerulonephritis with monoclonal IgG deposits associated with pure mesangial proliferative features.
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