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10.1309/AJCPN25NJTOUNPNF http://scihub22266oqcxt.onion/10.1309/AJCPN25NJTOUNPNF 25873501/?report=reader!4505928!25873501     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Clin+Pathol 2015 ; 143 (5): 672-82 Nephropedia Template TP {{tp|p=25873501|t=2015. Extensive survey of STAT6 expression in a large series of mesenchymal tumors |pdf=|usr=}}{{25873501}} gab.com Text Extensive survey of STAT6 expression in a large series of mesenchymal tumors JO: Am J Clin Pathol http://www.kidney.de/pget.php?&tw=1&pmid=25873501 #FOAvip OBJECTIVES: Expression of strong nuclear STAT6 is thought to be a specific marker for solitary fibrous tumors (SFTs). Little is known about subtle expression patterns in other mesenchymal lesions. METHODS: We performed immunohistochemical studies against the C-terminus of STAT6 in tissue microarrays and whole sections, comprising 2366 mesenchymal lesions. RESULTS: Strong nuclear STAT6 was expressed in 285 of 2,021 tumors, including 206 of 240 SFTs, 49 of 408 well-differentiated/dedifferentiated liposarcomas, eight of 65 unclassified sarcomas, and 14 of 184 desmoid tumors, among others. Expression in SFTs was predominately limited to the nucleus. Other positive tumors typically expressed both nuclear and cytoplasmic STAT6. Complete absence of STAT6 was most common in pleomorphic liposarcoma and alveolar soft part sarcoma (60% and 72% cases negative, respectively). CONCLUSIONS: Strong nuclear STAT6 is largely specific for SFTs. Physiologic low-level cytoplasmic/nuclear expression is common in mesenchymal neoplasia and is of uncertain significance. Twit Text FOAVip Extensive survey of STAT6 expression in a large series of mesenchymal tumors ????Am J Clin Pathol http://www.kidney.de/pget.php?&tw=1&pmid=25873501 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25873501 #FOAvip English Wikipedia <ref>{{Cite pmid|25873501}}</ref> Extensive survey of STAT6 expression in a large series of mesenchymal tumors #MMPMID25873501 Demicco EG; Harms PW; Patel RM; Smith SC; Ingram D; Torres K; Carskadon SL; Camelo-Piragua S; McHugh JB; Siddiqui J; Palanisamy N; Lucas DR; Lazar AJ; Wang WL Am J Clin Pathol 2015[May]; 143 (5): 672-82 PMID25873501show ga OBJECTIVES: Expression of strong nuclear STAT6 is thought to be a specific marker for solitary fibrous tumors (SFTs). Little is known about subtle expression patterns in other mesenchymal lesions. METHODS: We performed immunohistochemical studies against the C-terminus of STAT6 in tissue microarrays and whole sections, comprising 2366 mesenchymal lesions. RESULTS: Strong nuclear STAT6 was expressed in 285 of 2,021 tumors, including 206 of 240 SFTs, 49 of 408 well-differentiated/dedifferentiated liposarcomas, eight of 65 unclassified sarcomas, and 14 of 184 desmoid tumors, among others. Expression in SFTs was predominately limited to the nucleus. Other positive tumors typically expressed both nuclear and cytoplasmic STAT6. Complete absence of STAT6 was most common in pleomorphic liposarcoma and alveolar soft part sarcoma (60% and 72% cases negative, respectively). CONCLUSIONS: Strong nuclear STAT6 is largely specific for SFTs. Physiologic low-level cytoplasmic/nuclear expression is common in mesenchymal neoplasia and is of uncertain significance. |Biomarkers, Tumor/*metabolism[MESH] |Cell Nucleus/metabolism[MESH] |Child[MESH] |Child, Preschool[MESH] |Humans[MESH] |Immunohistochemistry[MESH] |Liposarcoma/*metabolism/pathology[MESH] |STAT6 Transcription Factor/*metabolism[MESH] |Sarcoma/*metabolism/pathology[MESH] |Sensitivity and Specificity[MESH] |Soft Tissue Neoplasms/*metabolism/pathology[MESH] |Solitary Fibrous Tumors/*metabolism/pathology[MESH]Extensive survey of STAT6 expression in a large series of mesenchymal (epmc).pdf DeepDyve Pubget Overpricing