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10.1016/j.jns.2015.01.017 http://scihub22266oqcxt.onion/10.1016/j.jns.2015.01.017 25626769!ä!25626769 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Neurol+Sci 2015 ; 349 (1-2): 190-5 Nephropedia Template TP {{tp|p=25626769|t=2015. Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy |pdf=|usr=}}{{25626769}} gab.com Text Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy JO: J Neurol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25626769 #FOAvip We examined serum levels of various cytokines, chemokines, growth factors, and adhesion molecules in patients with uncomplicated influenza (n=20) and influenza virus-associated encephalopathy (IE) (n=18) to understand the underlying mechanism of IE. We found that IL-1beta, IL-2, IL-5, IL-6, IL-7, IL-8, IL-10, IL-13, G-CSF, GM-CSF, TNF-alpha, TIMP-1, MMP-9, sE-selectin, and neutrophil elastase were elevated significantly in sera from patients with uncomplicated influenza and those with IE, compared with normal controls (n=20). Of note, neutrophil elastase, sE-selectin, IL-8, and IL-13 were elevated significantly in IE as compared with uncomplicated influenza. In the present study, for the first time, we found that serum levels of neutrophil elastase were increased in patients with IE compared with uncomplicated influenza, which suggested that cerebral endothelial damage in the development of IE was mediated by neutrophil elastase. The present study implied that anti-elastase agents are possibly an effective therapeutic protocol for IE, but this needs further elucidation. Twit Text FOAVip Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy ????J Neurol Sci http://www.kidney.de/pget.php?&tw=1&pmid=25626769 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25626769 #FOAvip English Wikipedia <ref>{{Cite pmid|25626769}}</ref> Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy #MMPMID25626769 Sun G; Ota C; Kitaoka S; Chiba Y; Takayanagi M; Kitamura T; Yamamoto K; Fujie H; Mikami H; Uematsu M; Hino-Fukuyo N; Munakata M; Kure S; Haginoya K J Neurol Sci 2015[Feb]; 349 (1-2): 190-5 PMID25626769show ga We examined serum levels of various cytokines, chemokines, growth factors, and adhesion molecules in patients with uncomplicated influenza (n=20) and influenza virus-associated encephalopathy (IE) (n=18) to understand the underlying mechanism of IE. We found that IL-1beta, IL-2, IL-5, IL-6, IL-7, IL-8, IL-10, IL-13, G-CSF, GM-CSF, TNF-alpha, TIMP-1, MMP-9, sE-selectin, and neutrophil elastase were elevated significantly in sera from patients with uncomplicated influenza and those with IE, compared with normal controls (n=20). Of note, neutrophil elastase, sE-selectin, IL-8, and IL-13 were elevated significantly in IE as compared with uncomplicated influenza. In the present study, for the first time, we found that serum levels of neutrophil elastase were increased in patients with IE compared with uncomplicated influenza, which suggested that cerebral endothelial damage in the development of IE was mediated by neutrophil elastase. The present study implied that anti-elastase agents are possibly an effective therapeutic protocol for IE, but this needs further elucidation. |Child[MESH] |Child, Preschool[MESH] |Cytokines/blood[MESH] |E-Selectin/blood[MESH] |Encephalitis, Viral/blood/*immunology/metabolism[MESH] |Female[MESH] |Granulocyte Colony-Stimulating Factor/blood[MESH] |Granulocyte-Macrophage Colony-Stimulating Factor/blood[MESH] |Humans[MESH] |Infant[MESH] |Influenza, Human/blood/*immunology/metabolism/virology[MESH] |Interleukin-10/blood[MESH] |Interleukin-13/blood[MESH] |Interleukin-1beta/blood[MESH] |Interleukin-2/blood[MESH] |Interleukin-5/blood[MESH] |Interleukin-6/blood[MESH] |Interleukin-7/blood[MESH] |Interleukin-8/blood[MESH] |Leukocyte Elastase/*blood[MESH] |Male[MESH] |Tissue Inhibitor of Metalloproteinase-1/blood[MESH]Elevated serum levels of neutrophil elastase in patients with influenz(epmc).pdf DeepDyve Pubget Overpricing