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10.2215/CJN.05920613

http://scihub22266oqcxt.onion/10.2215/CJN.05920613
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24855283!4255408!24855283
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suck abstract from ncbi

pmid24855283      Clin+J+Am+Soc+Nephrol 2014 ; 9 (12): 2147-63
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  • Distal convoluted tubule #MMPMID24855283
  • Subramanya AR; Ellison DH
  • Clin J Am Soc Nephrol 2014[Dec]; 9 (12): 2147-63 PMID24855283show ga
  • The distal convoluted tubule is the nephron segment that lies immediately downstream of the macula densa. Although short in length, the distal convoluted tubule plays a critical role in sodium, potassium, and divalent cation homeostasis. Recent genetic and physiologic studies have greatly expanded our understanding of how the distal convoluted tubule regulates these processes at the molecular level. This article provides an update on the distal convoluted tubule, highlighting concepts and pathophysiology relevant to clinical practice.
  • |Calcium/metabolism[MESH]
  • |Cations, Divalent/*metabolism[MESH]
  • |Epithelial Sodium Channels/metabolism[MESH]
  • |Humans[MESH]
  • |Kidney Tubules, Distal/anatomy & histology/metabolism/*physiology[MESH]
  • |Magnesium/metabolism[MESH]
  • |Potassium Channels, Inwardly Rectifying/metabolism[MESH]
  • |Potassium/*metabolism[MESH]
  • |Protein Serine-Threonine Kinases/metabolism[MESH]
  • |Renal Reabsorption/*physiology[MESH]
  • |Signal Transduction[MESH]
  • |Sodium Chloride/*metabolism[MESH]
  • |Sodium/*metabolism[MESH]


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