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10.1007/s10517-014-2463-7

http://scihub22266oqcxt.onion/10.1007/s10517-014-2463-7
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24824710!ä!24824710

suck abstract from ncbi


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pmid24824710      Bull+Exp+Biol+Med 2014 ; 156 (6): 833-7
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  • Expression of profibrotic growth factors and their receptors by mouse lung macrophages and fibroblasts under conditions of acute viral inflammation in influenza A/H5N1 virus #MMPMID24824710
  • Anikina AG; Shkurupii VA; Potapova OV; Kovner AV; Shestopalov AM
  • Bull Exp Biol Med 2014[Apr]; 156 (6): 833-7 PMID24824710show ga
  • Morphological signs of early interstitial fibrosis, developing under conditions of acute viral inflammation (postinfection days 1-14), were observed in C57Bl/6 mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus. The development of fibrosis was confirmed by an increase in the number of lung cells expressing TNF-alpha. These changes were recorded in the presence of a many-fold increase in the counts of macrophages and fibroblasts expressing FGF, EGF, and their receptors.
  • |*Influenza A Virus, H5N1 Subtype[MESH]
  • |Animals[MESH]
  • |Epidermal Growth Factor/metabolism[MESH]
  • |ErbB Receptors/metabolism[MESH]
  • |Fibroblast Growth Factors/metabolism[MESH]
  • |Fibroblasts/*metabolism[MESH]
  • |Histological Techniques[MESH]
  • |Immunohistochemistry[MESH]
  • |Macrophages, Alveolar/*metabolism[MESH]
  • |Male[MESH]
  • |Mice[MESH]
  • |Mice, Inbred C57BL[MESH]
  • |Orthomyxoviridae Infections/complications/*metabolism[MESH]
  • |Pulmonary Fibrosis/etiology/*metabolism[MESH]


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