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Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Bull+Exp+Biol+Med 2014 ; 156 (6): 736-9 Nephropedia Template TP
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Patterns of TRPM7 expression in hypothalamic and hippocampal neurons in modeling of nutritional magnesium deficiency #MMPMID24824683
Bull Exp Biol Med 2014[Apr]; 156 (6): 736-9 PMID24824683show ga
Patterns of expression of TRPM7, the major cellular magnesium transporters in neurons of the hypothalamic region and hippocampus, were studied immunohistochemically. Multidirectional nature and different levels of the expression of the above antigen were revealed during modeled magnesium deficiency with regard to structural and functional features of neuron organization in the hypothalamic paraventricular and supraoptic nuclei as well as hippocampal field CA1 and CA3. Changes in the structural characteristics of neurons in the studied areas (absolute and relative indicators) and TRPM7 expression patterns were quantitatively analyzed considering the data on the role of the studied antigen in magnesium homeostasis, cell damage, and compensation.