Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1177/1091581814530764 http://scihub22266oqcxt.onion/10.1177/1091581814530764 24728861!ä!24728861 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Toxicol 2014 ; 33 (3): 155-161 Nephropedia Template TP {{tp|p=24728861|t=2014. Aflatoxin B1-Induced Reproductive Toxicity in Male Rats: Possible Mechanism of Action |pdf=|usr=}}{{24728861}} gab.com Text Aflatoxin B1-Induced Reproductive Toxicity in Male Rats: Possible Mechanism of Action JO: Int J Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=24728861 #FOAvip Aflatoxin B1 (AFB1), one of the most common mycotoxins found in human foods, is principally hepatotoxic; however, it also affects reproduction. The aim of the present study was to elucidate the reproductive toxic effects and possible mechanism of action of AFB1 in rats. Male Wistar rats were injected intramuscularly with doses of 10, 20, or 50 microg AFB1/kg body weight on alternate days from 45 to 100 days of age. Significant reductions in body weights, relative weights of reproductive organs, daily sperm production, epididymal sperm count, viable sperm, motile sperm, and hypoosmotic swelling-tail coiled sperm were observed. Significant decreases in testicular steroidogenic enzymes and serum testosterone levels were also observed indicating decreased steroidogenesis. In silico docking studies illustrated AFB1 binds with steroidogenic acute regulatory (StAR) protein thereby affecting the transport of cholesterol into mitochondria resulting in decreased steroidogenesis. Twit Text FOAVip Aflatoxin B1-Induced Reproductive Toxicity in Male Rats: Possible Mechanism of Action ????Int J Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=24728861 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24728861 #FOAvip English Wikipedia <ref>{{Cite pmid|24728861}}</ref> Aflatoxin B1-Induced Reproductive Toxicity in Male Rats: Possible Mechanism of Action #MMPMID24728861 Supriya C; Girish BP; Reddy PS Int J Toxicol 2014[May]; 33 (3): 155-161 PMID24728861show ga Aflatoxin B1 (AFB1), one of the most common mycotoxins found in human foods, is principally hepatotoxic; however, it also affects reproduction. The aim of the present study was to elucidate the reproductive toxic effects and possible mechanism of action of AFB1 in rats. Male Wistar rats were injected intramuscularly with doses of 10, 20, or 50 microg AFB1/kg body weight on alternate days from 45 to 100 days of age. Significant reductions in body weights, relative weights of reproductive organs, daily sperm production, epididymal sperm count, viable sperm, motile sperm, and hypoosmotic swelling-tail coiled sperm were observed. Significant decreases in testicular steroidogenic enzymes and serum testosterone levels were also observed indicating decreased steroidogenesis. In silico docking studies illustrated AFB1 binds with steroidogenic acute regulatory (StAR) protein thereby affecting the transport of cholesterol into mitochondria resulting in decreased steroidogenesis. |*Models, Molecular[MESH] |Acinetobacter baumannii/enzymology[MESH] |Aflatoxin B1/administration & dosage/chemistry/metabolism/*toxicity[MESH] |Animals[MESH] |Bacterial Proteins/chemistry/metabolism[MESH] |Binding Sites[MESH] |Dose-Response Relationship, Drug[MESH] |Epididymis/drug effects/metabolism/pathology[MESH] |Hydrophobic and Hydrophilic Interactions[MESH] |Infertility, Male/*chemically induced/metabolism/pathology[MESH] |Male[MESH] |Molecular Conformation[MESH] |Molecular Docking Simulation[MESH] |Nucleotidyltransferases/chemistry/*metabolism[MESH] |Organ Size/drug effects[MESH] |Phosphoproteins/chemistry/*metabolism[MESH] |Protein Conformation[MESH] |Random Allocation[MESH] |Rats, Wistar[MESH] |Spermatogenesis/*drug effects[MESH] |Testis/*drug effects/metabolism/pathology[MESH]Aflatoxin B1-Induced Reproductive Toxicity in Male Rats: Possible Mech(epmc).pdf DeepDyve Pubget Overpricing