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10.1111/1469-0691.12525

http://scihub22266oqcxt.onion/10.1111/1469-0691.12525
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24382326!7128668!24382326
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suck abstract from ncbi


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pmid24382326      Clin+Microbiol+Infect 2014 ; 20 (9): O578-84
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  • Epidemiology of viral respiratory infections in a tertiary care centre in the era of molecular diagnosis, Geneva, Switzerland, 2011-2012 #MMPMID24382326
  • Ambrosioni J; Bridevaux PO; Wagner G; Mamin A; Kaiser L
  • Clin Microbiol Infect 2014[Sep]; 20 (9): O578-84 PMID24382326show ga
  • Few studies have examined the epidemiology of respiratory viral infections in large tertiary centres over more than one season in the era of molecular diagnosis. Respiratory clinical specimens received between 1 January 2011 and 31 December 2012 were analysed. Respiratory virus testing was performed using a large panel of real-time PCR or RT-PCR. Results were analysed according to sample type (upper versus lower respiratory tract) and age group. In all, 2996 (2469 (82.4%) upper; 527 (17.6%) lower) specimens were analysed. Overall positivity rate was 47.4% and 23.7% for upper and lower respiratory samples, respectively. The highest positivity rate was observed in patients under 18 years old (p <0.001); picornaviruses were the most frequent viruses detected over the year. Influenza virus, respiratory syncytial virus, human metapneumovirus and coronaviruses showed a seasonal peak during the winter season, while picornaviruses and adenoviruses were less frequently detected in these periods. Multiple viral infections were identified in 12% of positive cases and were significantly more frequent in children (p <0.001). In conclusion, we observed significant differences in viral infection rates and virus types among age groups, clinical sample types and seasons. Follow-up of viral detection over several seasons allows a better understanding of respiratory viral epidemiology.
  • |*Molecular Diagnostic Techniques[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Coinfection/epidemiology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Prevalence[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |Respiratory Tract Infections/*epidemiology/*virology[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |Switzerland/epidemiology[MESH]
  • |Tertiary Care Centers[MESH]
  • |Virus Diseases/*epidemiology/*virology[MESH]
  • |Viruses/*classification/genetics/*isolation & purification[MESH]


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