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10.1007/s10517-013-2265-3

http://scihub22266oqcxt.onion/10.1007/s10517-013-2265-3
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24319704!ä!24319704

suck abstract from ncbi


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pmid24319704      Bull+Exp+Biol+Med 2013 ; 156 (1): 11-4
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  • Role of matrix metalloproteinases and their inhibitor in the development of early pulmonary fibrosis in mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus #MMPMID24319704
  • Anikina AG; Potapova OV; Shkurupii VA; Shestopalov AM
  • Bull Exp Biol Med 2013[Nov]; 156 (1): 11-4 PMID24319704show ga
  • High levels of macrophages and fibroblasts expressing MMP-2, MMP-9, and MMP-10 against the background of progressing early fibrosis of the lungs (manifesting in an increase in volume density of type I, III, IV, and VI collagens) were found in C57Bl/6 mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus. Progressing fibrosis of the lungs in infected mice was associated with imbalance of collagen synthesis and degradation processes conjugated with high levels of macrophages and fibroblasts expressing TIMP-2.
  • |*Influenza A Virus, H5N1 Subtype[MESH]
  • |Animals[MESH]
  • |Collagen/metabolism[MESH]
  • |Fibroblasts/enzymology[MESH]
  • |Macrophages, Alveolar/enzymology[MESH]
  • |Male[MESH]
  • |Matrix Metalloproteinases, Secreted/*metabolism[MESH]
  • |Mice[MESH]
  • |Mice, Inbred C57BL[MESH]
  • |Pulmonary Fibrosis/*enzymology/virology[MESH]
  • |Respiratory Tract Infections/*enzymology/virology[MESH]


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