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10.1093/ckj/sft044 http://scihub22266oqcxt.onion/10.1093/ckj/sft044 24282629!3840817!24282629     free     free     free       Clin+Kidney+J 2013 ; 6 (3): 327-329 Nephropedia Template TP {{tp|p=24282629|t=2013. Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib |pdf=|usr=}}{{24282629}} gab.com Text Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib JO: Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=24282629 #FOAvip Extracapillary-proliferative glomerulonephritis is a rare complication of multiple myeloma. Partial remission of kidney involvement with cyclophosphamide therapy has previously been described. We report the case of a 60-year-old male patient diagnosed with rapidly progressive glomerulonephritis associated with IgG kappa monoclonal gammopathy. His kidney biopsy revealed pauci-immune extracapillary-proliferative glomerulonephritis without cryoglobulinaemia. Treatment with the proteasome inhibitor bortezomib induced rapid clinical and histological remission of his kidney disease. The patient's renal function remained stable on bortezomib maintenance therapy. Our findings suggest that bortezomib is a promising therapeutic approach to ameliorate severe kidney damage in monoclonal gammopathy- and myeloma-associated pauci-immune extracapillary-proliferative glomerulonephritis. Twit Text FOAVip Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib ????Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=24282629 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24282629 #FOAvip English Wikipedia <ref>{{Cite pmid|24282629}}</ref> Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib #MMPMID24282629 Grundmann F; Witthus M; Gobel H; Kisner T; Siewert R; Benzing T; Kurschat CE Clin Kidney J 2013[Jun]; 6 (3): 327-329 PMID24282629show ga Extracapillary-proliferative glomerulonephritis is a rare complication of multiple myeloma. Partial remission of kidney involvement with cyclophosphamide therapy has previously been described. We report the case of a 60-year-old male patient diagnosed with rapidly progressive glomerulonephritis associated with IgG kappa monoclonal gammopathy. His kidney biopsy revealed pauci-immune extracapillary-proliferative glomerulonephritis without cryoglobulinaemia. Treatment with the proteasome inhibitor bortezomib induced rapid clinical and histological remission of his kidney disease. The patient's renal function remained stable on bortezomib maintenance therapy. Our findings suggest that bortezomib is a promising therapeutic approach to ameliorate severe kidney damage in monoclonal gammopathy- and myeloma-associated pauci-immune extracapillary-proliferative glomerulonephritis. ?Monoclonal gammopathy-associated pauci-immune extracapillary-prolifera(epmc).pdf DeepDyve Pubget Overpricing