Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

http://scihub22266oqcxt.onion/ 2426319!ä!2426319 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cyclic+Nucleotide+Protein+Phosphor+Res 1986 ; 11 (2): 87-97 Nephropedia Template TP {{tp|p=2426319|t=1986. Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase?|pdf=|usr=}}{{2426319}} gab.com Text Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase JO: J Cyclic Nucleotide Protein Phosphor Res http://www.kidney.de/pget.php?&tw=1&pmid=2426319 #FOAvip Porins interact with macrophage membranes and inhibit their phagocyting activity. We have tested the porin effect on a biologically relevant membrane-bound enzymic activity, the adenylate cyclase system, which appears to be stimulated both in the presence of Mn2+ and Mg2+ or Mg2+ + Gpp(NH)p. Moreover, for mice macrophages incubated in the presence of porins, there is an increase in the intracellular cAMP content after 5 min of incubation, with a maximum after 15 min of incubation. The results shown suggest that the porin effects on the adenylate cyclase can represent the molecular basis of the porin-dependent inhibition of the macrophages phagocytosis. Our point of view, which proposes a cAMP role in inhibiting the phagocyting activity in macrophages, is supported also by the results of the experiments carried out in the presence of both dibutyryl-cAMP or aminophylline. The phagocyting activity is inhibited in all cases and independently of the bacteria to be phagocyted. Twit Text FOAVip Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase ????J Cyclic Nucleotide Protein Phosphor Res http://www.kidney.de/pget.php?&tw=1&pmid=2426319 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2426319 #FOAvip English Wikipedia <ref>{{Cite pmid|2426319}}</ref> Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase? #MMPMID2426319 Di Donato A; Draetta GF; Illiano G; Tufano MA; Sommese L; Galdiero F J Cyclic Nucleotide Protein Phosphor Res 1986[]; 11 (2): 87-97 PMID2426319show ga Porins interact with macrophage membranes and inhibit their phagocyting activity. We have tested the porin effect on a biologically relevant membrane-bound enzymic activity, the adenylate cyclase system, which appears to be stimulated both in the presence of Mn2+ and Mg2+ or Mg2+ + Gpp(NH)p. Moreover, for mice macrophages incubated in the presence of porins, there is an increase in the intracellular cAMP content after 5 min of incubation, with a maximum after 15 min of incubation. The results shown suggest that the porin effects on the adenylate cyclase can represent the molecular basis of the porin-dependent inhibition of the macrophages phagocytosis. Our point of view, which proposes a cAMP role in inhibiting the phagocyting activity in macrophages, is supported also by the results of the experiments carried out in the presence of both dibutyryl-cAMP or aminophylline. The phagocyting activity is inhibited in all cases and independently of the bacteria to be phagocyted. |Adenylyl Cyclases/*metabolism[MESH] |Aminophylline/pharmacology[MESH] |Animals[MESH] |Bacterial Outer Membrane Proteins/isolation & purification/*pharmacology[MESH] |Bucladesine/pharmacology[MESH] |Cyclic AMP/metabolism[MESH] |Guanylyl Imidodiphosphate/pharmacology[MESH] |Ion Channels/physiology[MESH] |Kinetics[MESH] |Macrophages/enzymology/*physiology[MESH] |Magnesium/pharmacology[MESH] |Mice[MESH] |Phagocytosis/*drug effects[MESH]Do porins inhibit the macrophage phagocyting activity by stimulating t(epmc).pdf DeepDyve Pubget Overpricing