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10.1007/s00467-013-2666-6 http://scihub22266oqcxt.onion/10.1007/s00467-013-2666-6 24253590!4028442!24253590     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Nephrol 2015 ; 30 (12): 2085-98 Nephropedia Template TP {{tp|p=24253590|t=2015. Developmental changes in renal tubular transport-an overview |pdf=|usr=}}{{24253590}} gab.com Text Developmental changes in renal tubular transport-an overview JO: Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24253590 #FOAvip The adult kidney maintains a constant volume and composition of extracellular fluid despite changes in water and salt intake. The neonate is born with a kidney that has a small fraction of the glomerular filtration rate of the adult and immature tubules that function at a lower capacity than that of the mature animal. Nonetheless, the neonate is also able to maintain a constant extracellular fluid volume and composition. Postnatal renal tubular development was once thought to be due to an increase in the transporter abundance to meet the developmental increase in glomerular filtration rate. However, postnatal renal development of each nephron segment is quite complex. There are isoform changes of several transporters as well as developmental changes in signal transduction that affect the capacity of renal tubules to reabsorb solutes and water. This review will discuss neonatal tubular function with an emphasis on the differences that have been found between the neonate and adult. We will also discuss some of the factors that are responsible for the maturational changes in tubular transport that occur during postnatal renal development. Twit Text FOAVip Developmental changes in renal tubular transport-an overview ????Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24253590 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24253590 #FOAvip English Wikipedia <ref>{{Cite pmid|24253590}}</ref> Developmental changes in renal tubular transport-an overview #MMPMID24253590 Gattineni J; Baum M Pediatr Nephrol 2015[Dec]; 30 (12): 2085-98 PMID24253590show ga The adult kidney maintains a constant volume and composition of extracellular fluid despite changes in water and salt intake. The neonate is born with a kidney that has a small fraction of the glomerular filtration rate of the adult and immature tubules that function at a lower capacity than that of the mature animal. Nonetheless, the neonate is also able to maintain a constant extracellular fluid volume and composition. Postnatal renal tubular development was once thought to be due to an increase in the transporter abundance to meet the developmental increase in glomerular filtration rate. However, postnatal renal development of each nephron segment is quite complex. There are isoform changes of several transporters as well as developmental changes in signal transduction that affect the capacity of renal tubules to reabsorb solutes and water. This review will discuss neonatal tubular function with an emphasis on the differences that have been found between the neonate and adult. We will also discuss some of the factors that are responsible for the maturational changes in tubular transport that occur during postnatal renal development. |Animals[MESH] |Biological Transport/*physiology[MESH] |Glomerular Filtration Rate[MESH] |Humans[MESH] |Kidney Tubules/growth & development/*physiology[MESH] |Kidney/*growth & development[MESH]Developmental changes in renal tubular transport-an overview (epmc).pdf DeepDyve Pubget Overpricing