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10.1016/j.virol.2013.06.022

http://scihub22266oqcxt.onion/10.1016/j.virol.2013.06.022
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24074579!ä!24074579

suck abstract from ncbi


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pmid24074579      Virology 2013 ; 446 (1-2): 173-9
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  • Human parvovirus B19 infection leads to downregulation of thyroid, estrogen, and retinoid hormone receptor expression #MMPMID24074579
  • Ignatovich IV; Hobbs JA
  • Virology 2013[Nov]; 446 (1-2): 173-9 PMID24074579show ga
  • Erythrovirus B19 (B19V) is a member of the family Parvoviridae. Infection with B19V has been linked to a variety of diseases including erythroid, thyroid, neurological and autoimmune diseases. Here we show that infection of primary CD36+ cells with B19V coincides with downregulation of thyroid, retinoid, and estrogen hormone receptors. In addition we show changes in expression of a variety of related downstream signaling genes participating in cancer and cardiac-related diseases in B19V-infected erythroid primary cells.
  • |*Host-Pathogen Interactions[MESH]
  • |*Virus Replication[MESH]
  • |CD36 Antigens/analysis[MESH]
  • |Cells, Cultured[MESH]
  • |Down-Regulation[MESH]
  • |Humans[MESH]
  • |Myeloid Progenitor Cells/chemistry/*virology[MESH]
  • |Parvovirus B19, Human/*physiology[MESH]
  • |Receptors, Estrogen/*biosynthesis[MESH]
  • |Receptors, Retinoic Acid/*biosynthesis[MESH]
  • |Receptors, Thyroid Hormone/*biosynthesis[MESH]


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