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10.1111/sji.12107 http://scihub22266oqcxt.onion/10.1111/sji.12107 24006947!7169485!24006947     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Scand+J+Immunol 2013 ; 78 (5): 395-400 Nephropedia Template TP {{tp|p=24006947|t=2013. Type I IFN exhaustion is a host defence protecting against secondary bacterial infections |pdf=|usr=}}{{24006947}} gab.com Text Type I IFN exhaustion is a host defence protecting against secondary bacterial infections JO: Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24006947 #FOAvip Type I interferons (IFN-I) have been known for decades for their indispensable role in curtailing viral infections. It is, however, now also increasingly recognized that IFN-I is detrimental to the host in combating a number of bacterial infections. We have previously reported that viral infections induce partial lymphocyte activation, characterized by significant increases in the cell surface expression of CD69 and CD86, but not CD25. This systemic partial activation of lymphocytes, mediated by IFN-I, is rapid and is followed by a period of IFN-I unresponsiveness. Here we propose that IFN-I exhaustion that occurs soon after a primary viral infection may be a host response protecting it from secondary bacterial infections. Twit Text FOAVip Type I IFN exhaustion is a host defence protecting against secondary bacterial infections ????Scand J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=24006947 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24006947 #FOAvip English Wikipedia <ref>{{Cite pmid|24006947}}</ref> Type I IFN exhaustion is a host defence protecting against secondary bacterial infections #MMPMID24006947 Furuya Y; Mullbacher A Scand J Immunol 2013[Nov]; 78 (5): 395-400 PMID24006947show ga Type I interferons (IFN-I) have been known for decades for their indispensable role in curtailing viral infections. It is, however, now also increasingly recognized that IFN-I is detrimental to the host in combating a number of bacterial infections. We have previously reported that viral infections induce partial lymphocyte activation, characterized by significant increases in the cell surface expression of CD69 and CD86, but not CD25. This systemic partial activation of lymphocytes, mediated by IFN-I, is rapid and is followed by a period of IFN-I unresponsiveness. Here we propose that IFN-I exhaustion that occurs soon after a primary viral infection may be a host response protecting it from secondary bacterial infections. |Animals[MESH] |Bacterial Infections/*immunology[MESH] |Coinfection/*immunology[MESH] |Interferon Type I/*immunology[MESH] |Lymphocyte Activation/immunology[MESH] |Lymphocytes/immunology[MESH] |Mice[MESH]Type I IFN exhaustion is a host defence protecting against secondary b(epmc).pdf DeepDyve Pubget Overpricing