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10.1111/irv.12155 http://scihub22266oqcxt.onion/10.1111/irv.12155 23962134!4177805!23962134     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Influenza+Other+Respir+Viruses 2014 ; 8 (1): 116-22 Nephropedia Template TP {{tp|p=23962134|t=2014. Increased cytokine/chemokines in serum from asthmatic and non-asthmatic patients with viral respiratory infection |pdf=|usr=}}{{23962134}} gab.com Text Increased cytokine/chemokines in serum from asthmatic and non-asthmatic patients with viral respiratory infection JO: Influenza Other Respir Viruses http://www.kidney.de/pget.php?&tw=1&pmid=23962134 #FOAvip BACKGROUND: Respiratory viral infections can induce different cytokine/chemokine profiles in lung tissues and have a significant influence on patients with asthma. There is little information about the systemic cytokine status in viral respiratory-infected asthmatic patients compared with non-asthmatic patients. OBJECTIVES: The aim of this study was to determine changes in circulating cytokines (IL-1beta, TNF-alpha, IL-4, IL-5) and chemokines (MCP1: monocyte chemoattractant protein-1 and RANTES: regulated on activation normal T cell expressed and secreted) in patients with an asthmatic versus a non-asthmatic background with respiratory syncytial virus, parainfluenza virus or adenovirus respiratory infection. In addition, human monocyte cultures were incubated with respiratory viruses to determine the cytokine/chemokine profiles. PATIENTS/METHODS: Patients with asthmatic (n = 34) and non-asthmatic (n = 18) history and respiratory infections with respiratory syncytial virus, parainfluenza, and adenovirus were studied. Healthy individuals with similar age and sex (n = 10) were used as controls. Cytokine/chemokine content in blood and culture supernatants was determined by ELISA. Monocytes were isolated by Hystopaque gradient and cocultured with each of the above-mentioned viruses. RESULTS: Similar increased cytokine concentrations were observed in asthmatic and non-asthmatic patients. However, higher concentrations of chemokines were observed in asthmatic patients. Virus-infected monocyte cultures showed similar cytokine/chemokine profiles to those observed in the patients. CONCLUSIONS: Circulating cytokine profiles induced by acute viral lung infection were not related to asthmatic status, except for chemokines that were already increased in the asthmatic status. Monocytes could play an important role in the increased circulating concentration of cytokines found during respiratory viral infections. Twit Text FOAVip Increased cytokine/chemokines in serum from asthmatic and non-asthmatic patients with viral respiratory infection ????Influenza Other Respir Viruses http://www.kidney.de/pget.php?&tw=1&pmid=23962134 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23962134 #FOAvip English Wikipedia <ref>{{Cite pmid|23962134}}</ref> Increased cytokine/chemokines in serum from asthmatic and non-asthmatic patients with viral respiratory infection #MMPMID23962134 Giuffrida MJ; Valero N; Mosquera J; Alvarez de Mon M; Chacin B; Espina LM; Gotera J; Bermudez J; Mavarez A Influenza Other Respir Viruses 2014[Jan]; 8 (1): 116-22 PMID23962134show ga BACKGROUND: Respiratory viral infections can induce different cytokine/chemokine profiles in lung tissues and have a significant influence on patients with asthma. There is little information about the systemic cytokine status in viral respiratory-infected asthmatic patients compared with non-asthmatic patients. OBJECTIVES: The aim of this study was to determine changes in circulating cytokines (IL-1beta, TNF-alpha, IL-4, IL-5) and chemokines (MCP1: monocyte chemoattractant protein-1 and RANTES: regulated on activation normal T cell expressed and secreted) in patients with an asthmatic versus a non-asthmatic background with respiratory syncytial virus, parainfluenza virus or adenovirus respiratory infection. In addition, human monocyte cultures were incubated with respiratory viruses to determine the cytokine/chemokine profiles. PATIENTS/METHODS: Patients with asthmatic (n = 34) and non-asthmatic (n = 18) history and respiratory infections with respiratory syncytial virus, parainfluenza, and adenovirus were studied. Healthy individuals with similar age and sex (n = 10) were used as controls. Cytokine/chemokine content in blood and culture supernatants was determined by ELISA. Monocytes were isolated by Hystopaque gradient and cocultured with each of the above-mentioned viruses. RESULTS: Similar increased cytokine concentrations were observed in asthmatic and non-asthmatic patients. However, higher concentrations of chemokines were observed in asthmatic patients. Virus-infected monocyte cultures showed similar cytokine/chemokine profiles to those observed in the patients. CONCLUSIONS: Circulating cytokine profiles induced by acute viral lung infection were not related to asthmatic status, except for chemokines that were already increased in the asthmatic status. Monocytes could play an important role in the increased circulating concentration of cytokines found during respiratory viral infections. |Adenoviridae Infections/*immunology/pathology[MESH] |Adenoviridae/immunology[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Asthma/complications[MESH] |Cells, Cultured[MESH] |Child[MESH] |Cytokines/*blood[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Monocytes/immunology[MESH] |Paramyxoviridae Infections/*immunology/pathology[MESH] |Respiratory Syncytial Virus Infections/*immunology/pathology[MESH] |Respiratory Syncytial Viruses/immunology[MESH] |Respiratory Tract Infections/*immunology/pathology[MESH] |Respirovirus/immunology[MESH] |Serum/chemistry[MESH]Increased cytokine/chemokines in serum from asthmatic and non-asthmati(epmc).pdf DeepDyve Pubget Overpricing