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10.1038/nri3494 http://scihub22266oqcxt.onion/10.1038/nri3494 23907446!3980848!23907446     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Immunol 2013 ; 13 (9): 666-78 Nephropedia Template TP {{tp|p=23907446|t=2013. MicroRNA-mediated regulation of T helper cell differentiation and plasticity |pdf=|usr=}}{{23907446}} gab.com Text MicroRNA-mediated regulation of T helper cell differentiation and plasticity JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=23907446 #FOAvip CD4(+) T helper (TH) cells regulate appropriate cellular and humoral immune responses to a wide range of pathogens and are central to the success of vaccines. However, their dysregulation can cause allergies and autoimmune diseases. The CD4(+) T cell population is characterized not only by a range of distinct cell subsets, such as TH1, TH2 and TH17 cells, regulatory T cells and T follicular helper cells--each with specific functions and gene expression programmes--but also by plasticity between the different TH cell subsets. In this Review, we discuss recent advances and emerging ideas about how microRNAs--small endogenously expressed oligonucleotides that modulate gene expression--are involved in the regulatory networks that determine TH cell fate decisions and that regulate their effector functions. Twit Text FOAVip MicroRNA-mediated regulation of T helper cell differentiation and plasticity ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=23907446 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23907446 #FOAvip English Wikipedia <ref>{{Cite pmid|23907446}}</ref> MicroRNA-mediated regulation of T helper cell differentiation and plasticity #MMPMID23907446 Baumjohann D; Ansel KM Nat Rev Immunol 2013[Sep]; 13 (9): 666-78 PMID23907446show ga CD4(+) T helper (TH) cells regulate appropriate cellular and humoral immune responses to a wide range of pathogens and are central to the success of vaccines. However, their dysregulation can cause allergies and autoimmune diseases. The CD4(+) T cell population is characterized not only by a range of distinct cell subsets, such as TH1, TH2 and TH17 cells, regulatory T cells and T follicular helper cells--each with specific functions and gene expression programmes--but also by plasticity between the different TH cell subsets. In this Review, we discuss recent advances and emerging ideas about how microRNAs--small endogenously expressed oligonucleotides that modulate gene expression--are involved in the regulatory networks that determine TH cell fate decisions and that regulate their effector functions. |Animals[MESH] |Cell Differentiation/genetics/immunology[MESH] |Cell Survival/immunology[MESH] |Gene Expression Regulation/immunology[MESH] |Humans[MESH] |Immune Tolerance/genetics/immunology[MESH] |Lymphocyte Activation/genetics/immunology[MESH] |MicroRNAs/genetics/*immunology[MESH]MicroRNA-mediated regulation of T helper cell differentiation and plas(epmc).pdf DeepDyve Pubget Overpricing