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10.1021/cn400090q http://scihub22266oqcxt.onion/10.1021/cn400090q 23883191/?report=reader!3750682!23883191     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Chem+Neurosci 2013 ; 4 (8): 1137-50 Nephropedia Template TP {{tp|p=23883191|t=2013. Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds |pdf=|usr=}}{{23883191}} gab.com Text Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds JO: ACS Chem Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=23883191 #FOAvip Among different classes of psychotropic drugs, hallucinogenic agents exert one of the most prominent effects on human and animal behaviors, markedly altering sensory, motor, affective, and cognitive responses. The growing clinical and preclinical interest in psychedelic, dissociative, and deliriant hallucinogens necessitates novel translational, sensitive, and high-throughput in vivo models and screens. Primate and rodent models have been traditionally used to study cellular mechanisms and neural circuits of hallucinogenic drugs' action. The utility of zebrafish ( Danio rerio ) in neuroscience research is rapidly growing due to their high physiological and genetic homology to humans, ease of genetic manipulation, robust behaviors, and cost effectiveness. Possessing a fully characterized genome, both adult and larval zebrafish are currently widely used for in vivo screening of various psychotropic compounds, including hallucinogens and related drugs. Recognizing the growing importance of hallucinogens in biological psychiatry, here we discuss hallucinogenic-induced phenotypes in zebrafish and evaluate their potential as efficient preclinical models of drug-induced states in humans. Twit Text FOAVip Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds ????ACS Chem Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=23883191 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23883191 #FOAvip English Wikipedia <ref>{{Cite pmid|23883191}}</ref> Perspectives on zebrafish models of hallucinogenic drugs and related psychotropic compounds #MMPMID23883191 Neelkantan N; Mikhaylova A; Stewart AM; Arnold R; Gjeloshi V; Kondaveeti D; Poudel MK; Kalueff AV ACS Chem Neurosci 2013[Aug]; 4 (8): 1137-50 PMID23883191show ga Among different classes of psychotropic drugs, hallucinogenic agents exert one of the most prominent effects on human and animal behaviors, markedly altering sensory, motor, affective, and cognitive responses. The growing clinical and preclinical interest in psychedelic, dissociative, and deliriant hallucinogens necessitates novel translational, sensitive, and high-throughput in vivo models and screens. Primate and rodent models have been traditionally used to study cellular mechanisms and neural circuits of hallucinogenic drugs' action. The utility of zebrafish ( Danio rerio ) in neuroscience research is rapidly growing due to their high physiological and genetic homology to humans, ease of genetic manipulation, robust behaviors, and cost effectiveness. Possessing a fully characterized genome, both adult and larval zebrafish are currently widely used for in vivo screening of various psychotropic compounds, including hallucinogens and related drugs. Recognizing the growing importance of hallucinogens in biological psychiatry, here we discuss hallucinogenic-induced phenotypes in zebrafish and evaluate their potential as efficient preclinical models of drug-induced states in humans. |*Disease Models, Animal[MESH] |Animals[MESH] |Anxiety/physiopathology[MESH] |Behavior, Animal/*drug effects/physiology[MESH] |Biomarkers/metabolism[MESH] |Biomedical Research/methods[MESH] |Cognition/drug effects/physiology[MESH] |Drug Evaluation, Preclinical[MESH] |Hallucinogens/*pharmacology[MESH] |Motor Activity/drug effects/physiology[MESH] |Phenotype[MESH] |Psychopharmacology/methods[MESH] |Psychotropic Drugs/*pharmacology[MESH] |Reward[MESH] |Social Behavior[MESH]Perspectives on zebrafish models of hallucinogenic drugs and related p(epmc).pdf DeepDyve Pubget Overpricing