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10.1111/acps.12170 http://scihub22266oqcxt.onion/10.1111/acps.12170 23837831/?report=reader!3797176!23837831     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23837831&cmd=llinks): Failed to open stream: HTTP request failed! 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Antecedents of manic versus other first psychotic episodes in 263 bipolar I disorder patients |pdf=|usr=}}{{23837831}} gab.com Text Antecedents of manic versus other first psychotic episodes in 263 bipolar I disorder patients JO: Acta Psychiatr Scand http://www.kidney.de/pget.php?&tw=1&pmid=23837831 #FOAvip OBJECTIVE: As initial episode type can predict later morbidity in bipolar disorder, we tested the hypothesis that clinical antecedents might predict initial episode types. METHOD: We studied 263 first-episode, adult, DSM-IV-TR type I bipolar disorder (BD-I) subjects within the McLean-Harvard-International First-Episode Project. Based on blinded assessments of antecedents from SCID examinations and clinical records, we compared first lifetime manic vs. other (mixed, depressive, or non-affective) major psychotic episodes. RESULTS: We identified 32 antecedents arising at early, intermediate or later times, starting 12.3+/-10.7 years prior to first lifetime major psychotic episodes. Based on multivariate modeling, antecedents associated significantly and independently with other (n=113) more than manic (n=150) first lifetime major psychotic episodes ranked by odds ratio: more early attentional disturbances, more late depression, more early perplexity, more detoxification, more early unstable mixed affects, more antidepressants, more early dysphoria, more intermediate depression, more early impulsivity, more late anhedonia, longer early-to-intermediate intervals, more intermediate substance abuse, more family history of major depression, and younger at earliest antecedents. Antecedents selectively preceding manic more than other first psychotic episodes included more late behavioral problems and more risk of familial BD-I. CONCLUSION: Clinical antecedents in adult, BD-I patients, beginning a decade before first major episodes and progressing through sequential stages were dissimilar in manic vs. other first psychotic episodes. Twit Text FOAVip Antecedents of manic versus other first psychotic episodes in 263 bipolar I disorder patients ????Acta Psychiatr Scand http://www.kidney.de/pget.php?&tw=1&pmid=23837831 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23837831 #FOAvip English Wikipedia <ref>{{Cite pmid|23837831}}</ref> Antecedents of manic versus other first psychotic episodes in 263 bipolar I disorder patients #MMPMID23837831 Salvatore P; Baldessarini RJ; Khalsa HM; Vazquez G; Perez J; Faedda GL; Amore M; Maggini C; Tohen M Acta Psychiatr Scand 2014[Apr]; 129 (4): 275-85 PMID23837831show ga OBJECTIVE: As initial episode type can predict later morbidity in bipolar disorder, we tested the hypothesis that clinical antecedents might predict initial episode types. METHOD: We studied 263 first-episode, adult, DSM-IV-TR type I bipolar disorder (BD-I) subjects within the McLean-Harvard-International First-Episode Project. Based on blinded assessments of antecedents from SCID examinations and clinical records, we compared first lifetime manic vs. other (mixed, depressive, or non-affective) major psychotic episodes. RESULTS: We identified 32 antecedents arising at early, intermediate or later times, starting 12.3+/-10.7 years prior to first lifetime major psychotic episodes. Based on multivariate modeling, antecedents associated significantly and independently with other (n=113) more than manic (n=150) first lifetime major psychotic episodes ranked by odds ratio: more early attentional disturbances, more late depression, more early perplexity, more detoxification, more early unstable mixed affects, more antidepressants, more early dysphoria, more intermediate depression, more early impulsivity, more late anhedonia, longer early-to-intermediate intervals, more intermediate substance abuse, more family history of major depression, and younger at earliest antecedents. Antecedents selectively preceding manic more than other first psychotic episodes included more late behavioral problems and more risk of familial BD-I. CONCLUSION: Clinical antecedents in adult, BD-I patients, beginning a decade before first major episodes and progressing through sequential stages were dissimilar in manic vs. other first psychotic episodes. |*Prodromal Symptoms[MESH] |Adult[MESH] |Bipolar Disorder/classification/*diagnosis/*physiopathology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Prognosis[MESH]Antecedents of manic versus other first psychotic episodes in 263 bipo(epmc).pdf DeepDyve Pubget Overpricing