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10.1590/abd1806-4841.20131595

http://scihub22266oqcxt.onion/10.1590/abd1806-4841.20131595
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suck abstract from ncbi


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pmid23793189      An+Bras+Dermatol 2013 ; 88 (3): 403-7
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  • Cartilaginous melanoma: case report and review of the literature #MMPMID23793189
  • Joana Devesa P; Labareda JM; Bartolo EA; Santos MF; Vale EM
  • An Bras Dermatol 2013[May]; 88 (3): 403-7 PMID23793189show ga
  • Malignant melanoma can present a variety of histopathological patterns. Cartilaginous change in the absence of osteogenic differentiation is extremely rare in malignant melanoma, being among the least frequent of the wide range of melanoma histologic patterns. We report a case of a 47-year-old woman with a subungual nodule on her right great toe for many years. Histopathological examination of the lesion led to a diagnosis of malignant melanoma with cartilaginous differentiation devoid of concomitant osseous areas. It would appear that this unusual form of melanoma has a predilection for acral location, particularly the subungual region. Malignant melanoma with chondroid stroma should therefore be considered in the differential diagnosis of cartilaginous lesions of the toes and fingers. Careful examination of the overlying epidermis and identification of an in situ component of melanoma may be necessary in order to establish the correct diagnosis.
  • |Biopsy[MESH]
  • |Cartilage/*pathology[MESH]
  • |Chondrocytes/pathology[MESH]
  • |Diagnosis, Differential[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Melanoma/*pathology[MESH]
  • |Middle Aged[MESH]
  • |Rare Diseases[MESH]
  • |S100 Proteins/analysis[MESH]
  • |Skin Neoplasms/*pathology[MESH]


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