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10.1111/1469-0691.12242 http://scihub22266oqcxt.onion/10.1111/1469-0691.12242 23663244!7129489!23663244     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Microbiol+Infect 2013 ; 19 (10): E435-42 Nephropedia Template TP {{tp|p=23663244|t=2013. The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features |pdf=|usr=}}{{23663244}} gab.com Text The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features JO: Clin Microbiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=23663244 #FOAvip Recent developments in molecular diagnostic tools have led to the easy and rapid detection of a large number of rhinovirus (HRV) strains. However, the lack of clinical and epidemiological data hampers the interpretation of these diagnostic findings. From October 2009 to January 2011, we conducted a prospective study in hospitalized children from whom samples were taken for the detection of respiratory viruses. Clinical, epidemiological and microbiological data from 644 patients with 904 disease episodes were collected. When HRV tested positive, strains were further characterized by sequencing the VP4/VP2 region of the HRV genome. HRV was the single respiratory virus detected in 254 disease episodes (28%). Overall, 99 different serotypes were detected (47% HRV-A, 12% HRV-B, 39% HRV-C). Patients with HRV had more underlying pulmonary illness compared with patients with no virus (p 0.01), or patients with another respiratory virus besides HRV (p 0.007). Furthermore, cough, shortness of breath and a need for oxygen were significantly more present in patients with HRV infection. Particularly, patients with HRV-B required extra oxygen. No respiratory symptom, except for oxygen need, was predictive of the presence of HRV. In 22% of HRV-positive disease episodes, HRV infection was hospital acquired. Phylogenetic analysis revealed several clusters of HRV; in more than 25% of these clusters epidemiological information was suggestive of transmission within specific wards. In conclusion, the detection of HRV may help in explaining respiratory illness, particular in patients with pulmonary co-morbidities. Identifying HRV provides opportunities for timely implementation of infection control measures to prevent intra-hospital transmission. Twit Text FOAVip The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features ????Clin Microbiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=23663244 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23663244 #FOAvip English Wikipedia <ref>{{Cite pmid|23663244}}</ref> The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features #MMPMID23663244 Rahamat-Langendoen JC; Riezebos-Brilman A; Hak E; Scholvinck EH; Niesters HG Clin Microbiol Infect 2013[Oct]; 19 (10): E435-42 PMID23663244show ga Recent developments in molecular diagnostic tools have led to the easy and rapid detection of a large number of rhinovirus (HRV) strains. However, the lack of clinical and epidemiological data hampers the interpretation of these diagnostic findings. From October 2009 to January 2011, we conducted a prospective study in hospitalized children from whom samples were taken for the detection of respiratory viruses. Clinical, epidemiological and microbiological data from 644 patients with 904 disease episodes were collected. When HRV tested positive, strains were further characterized by sequencing the VP4/VP2 region of the HRV genome. HRV was the single respiratory virus detected in 254 disease episodes (28%). Overall, 99 different serotypes were detected (47% HRV-A, 12% HRV-B, 39% HRV-C). Patients with HRV had more underlying pulmonary illness compared with patients with no virus (p 0.01), or patients with another respiratory virus besides HRV (p 0.007). Furthermore, cough, shortness of breath and a need for oxygen were significantly more present in patients with HRV infection. Particularly, patients with HRV-B required extra oxygen. No respiratory symptom, except for oxygen need, was predictive of the presence of HRV. In 22% of HRV-positive disease episodes, HRV infection was hospital acquired. Phylogenetic analysis revealed several clusters of HRV; in more than 25% of these clusters epidemiological information was suggestive of transmission within specific wards. In conclusion, the detection of HRV may help in explaining respiratory illness, particular in patients with pulmonary co-morbidities. Identifying HRV provides opportunities for timely implementation of infection control measures to prevent intra-hospital transmission. |Child, Preschool[MESH] |Cross Infection/epidemiology/*virology[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Infant[MESH] |Male[MESH] |Molecular Epidemiology[MESH] |Molecular Sequence Data[MESH] |Netherlands/epidemiology[MESH] |Phylogeny[MESH] |Picornaviridae Infections/epidemiology/*virology[MESH] |Prospective Studies[MESH]The significance of rhinovirus detection in hospitalized children: cli(epmc).pdf DeepDyve Pubget Overpricing