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10.1016/j.dci.2013.03.008

http://scihub22266oqcxt.onion/10.1016/j.dci.2013.03.008
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23542704!ä!23542704

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suck abstract from ncbi


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pmid23542704      Dev+Comp+Immunol 2013 ; 41 (3): 341-51
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  • Regulation of macrophage and dendritic cell function by pathogens and through immunomodulation in the avian mucosa #MMPMID23542704
  • de Geus ED; Vervelde L
  • Dev Comp Immunol 2013[Nov]; 41 (3): 341-51 PMID23542704show ga
  • Macrophages (MPh) and dendritic cells (DC) are members of the mononuclear phagocyte system. In chickens, markers to distinguish MPh from DC are lacking, but whether MPh and DC can be distinguished in humans and mice is under debate, despite the availability of numerous markers. Mucosal MPh and DC are strategically located to ingest foreign antigens, suggesting they can rapidly respond to invading pathogens. This review addresses our current understanding of DC and MPh function, the receptors expressed by MPh and DC involved in pathogen recognition, and the responses of DC and MPh against respiratory and intestinal pathogens in the chicken. Furthermore, potential opportunities are described to modulate MPh and DC responses to enhance disease resistance, highlighting modulation through nutraceuticals and vaccination.
  • |Animals[MESH]
  • |Chickens/*immunology[MESH]
  • |Coccidiosis/immunology/prevention & control[MESH]
  • |Dendritic Cells/*immunology/microbiology/parasitology/virology[MESH]
  • |Dietary Supplements/statistics & numerical data[MESH]
  • |Escherichia coli Infections/immunology/prevention & control[MESH]
  • |Gastrointestinal Tract/*immunology/microbiology/parasitology/virology[MESH]
  • |Immunity, Innate[MESH]
  • |Immunomodulation[MESH]
  • |Influenza in Birds/immunology/prevention & control[MESH]
  • |Lipopolysaccharide Receptors/genetics/immunology[MESH]
  • |Macrophages/*immunology/microbiology/parasitology/virology[MESH]
  • |Respiratory System/*immunology/microbiology/parasitology/virology[MESH]
  • |Sialic Acid Binding Immunoglobulin-like Lectins/genetics/immunology[MESH]


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