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10.1186/1751-0147-55-23

http://scihub22266oqcxt.onion/10.1186/1751-0147-55-23
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suck abstract from ncbi


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pmid23497714      Acta+Vet+Scand 2013 ; 55 (1): 23
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  • Clostridium difficile in faeces from healthy dogs and dogs with diarrhea #MMPMID23497714
  • Wetterwik KJ; Trowald-Wigh G; Fernstrom LL; Krovacek K
  • Acta Vet Scand 2013[Mar]; 55 (1): 23 PMID23497714show ga
  • BACKGROUND: This study was conducted to evaluate the faecal occurrence and characterization of Clostridium difficile in clinically healthy dogs (N = 50) and in dogs with diarrhea (N = 20) in the Stockholm-Uppsala region of Sweden. FINDINGS: Clostridium difficile was isolated from 2/50 healthy dogs and from 2/20 diarrheic dogs. Isolates from healthy dogs were negative for toxin A and B and for the tcdA and tcdB genes. Both isolates from diarrheic dogs were positive for toxin B and for the tcdA and tcdB genes. The C. difficile isolates from healthy dogs had PCR ribotype 009 (SE-type 6) and 010 (SE-type 3) whereas both isolates from dogs with diarrhoea had the toxigenic ribotype 014 (SE-type 21). One of the isolates from healthy dogs was initially resistant to metronidazole. CONCLUSIONS: This study revealed presence of toxigenic C. difficile in faecal samples of diarrheic dogs and low number of non- toxigenic isolates in healthy dogs from Uppsala-Stockholm region in Sweden. However, more comprehensive studies are warranted to investigate the role of C. difficile in gastrointestinal disease in dogs.
  • |Animals[MESH]
  • |Anti-Bacterial Agents/pharmacology[MESH]
  • |Clostridioides difficile/drug effects/genetics/*isolation & purification[MESH]
  • |Clostridium Infections/epidemiology/microbiology/*veterinary[MESH]
  • |Diarrhea/epidemiology/microbiology/*veterinary[MESH]
  • |Dog Diseases/epidemiology/*microbiology[MESH]
  • |Dogs[MESH]
  • |Drug Resistance, Bacterial[MESH]
  • |Feces/*microbiology[MESH]
  • |Ribotyping[MESH]


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