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10.1152/physiolgenomics.00143.2012 http://scihub22266oqcxt.onion/10.1152/physiolgenomics.00143.2012 23482811!3656420!23482811     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Physiol+Genomics 2013 ; 45 (9): 343-50 Nephropedia Template TP {{tp|p=23482811|t=2013. Strain-specific variations in cation content and transport in mouse erythrocytes |pdf=|usr=}}{{23482811}} gab.com Text Strain-specific variations in cation content and transport in mouse erythrocytes JO: Physiol Genomics http://www.kidney.de/pget.php?&tw=1&pmid=23482811 #FOAvip Studies of ion transport pathophysiology in hematological disorders and tests of possible new therapeutic agents for these disorders have been carried out in various mouse models because of close functional similarities between mouse and human red cells. We have explored strain-specific differences in erythrocyte membrane physiology in 10 inbred mouse strains by determining erythrocyte contents of Na(+), K(+), and Mg(2+), and erythrocyte transport of ions via the ouabain-sensitive Na-K pump, the amiloride-sensitive Na-H exchanger (NHE1), the volume and chloride-dependent K-Cl cotransporter (KCC), and the charybdotoxin-sensitive Gardos channel (KCNN4). Our data reveal substantial strain-specific and sex-specific differences in both ion content and trans-membrane ion transport in mouse erythrocytes. These differences demonstrate the feasibility of identifying specific quantitative trait loci for erythroid ion transport and content in genetically standardized inbred mouse strains. Twit Text FOAVip Strain-specific variations in cation content and transport in mouse erythrocytes ????Physiol Genomics http://www.kidney.de/pget.php?&tw=1&pmid=23482811 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23482811 #FOAvip English Wikipedia <ref>{{Cite pmid|23482811}}</ref> Strain-specific variations in cation content and transport in mouse erythrocytes #MMPMID23482811 Rivera A; Zee RY; Alper SL; Peters LL; Brugnara C Physiol Genomics 2013[May]; 45 (9): 343-50 PMID23482811show ga Studies of ion transport pathophysiology in hematological disorders and tests of possible new therapeutic agents for these disorders have been carried out in various mouse models because of close functional similarities between mouse and human red cells. We have explored strain-specific differences in erythrocyte membrane physiology in 10 inbred mouse strains by determining erythrocyte contents of Na(+), K(+), and Mg(2+), and erythrocyte transport of ions via the ouabain-sensitive Na-K pump, the amiloride-sensitive Na-H exchanger (NHE1), the volume and chloride-dependent K-Cl cotransporter (KCC), and the charybdotoxin-sensitive Gardos channel (KCNN4). Our data reveal substantial strain-specific and sex-specific differences in both ion content and trans-membrane ion transport in mouse erythrocytes. These differences demonstrate the feasibility of identifying specific quantitative trait loci for erythroid ion transport and content in genetically standardized inbred mouse strains. |Animals[MESH] |Cations/*metabolism[MESH] |Erythrocytes/*metabolism[MESH] |Female[MESH] |Humans[MESH] |Ion Transport[MESH] |K Cl- Cotransporters[MESH] |Male[MESH] |Mice[MESH] |Potassium/blood[MESH] |Sex Characteristics[MESH] |Sodium-Hydrogen Exchangers/metabolism[MESH] |Sodium-Potassium-Exchanging ATPase/metabolism[MESH] |Sodium/blood[MESH] |Species Specificity[MESH]Strain-specific variations in cation content and transport in mouse er(epmc).pdf DeepDyve Pubget Overpricing