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10.1007/s00586-013-2723-7

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suck abstract from ncbi


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pmid23455952      Eur+Spine+J 2013 ; 22 Suppl 3 (Suppl 3): S501-5
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  • Calcium pyrophosphate dihydrate deposition disease of the filum terminale #MMPMID23455952
  • Cacciotti G; Novegno F; Fiume D
  • Eur Spine J 2013[May]; 22 Suppl 3 (Suppl 3): S501-5 PMID23455952show ga
  • INTRODUCTION: Calcium pyrophosphate dihydrate crystal deposition disease (CPPDD) is a rare benign inflammatory joint disorder characterized by the presence of calcium pyrophosphate dihydrate crystal in the interarticular and periarticular tissue. It has been rarely described with spinal localization. METHODS: A 50-year-old woman, affected by CPPDD, presented a progressive weakness of both lower limbs associated with neurogenic claudication. Neuroradiological examinations revealed the presence of two intradural calcified lesions at level L3-L4, with no post-contrast enhancement. RESULTS: Surgery was performed and the histopathological exams documented the presence of rod-shaped crystals embedded in a fibrocartilaginous stroma. The postoperative course was uneventful and the patient experienced complete symptoms relief with a 5-year follow-up. CONCLUSION: Intradural CPPD localization at the filum terminale is an extremely rare occurrence. Total removal should be preferably attempted with a long-term focal control of the disease as we observed in our case.
  • |Cauda Equina/*pathology/surgery[MESH]
  • |Chondrocalcinosis/*pathology/surgery[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]


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