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The coming age of complete, accurate, and ubiquitous proteomes #MMPMID23438854
Mann M; Kulak NA; Nagaraj N; Cox J
Mol Cell 2013[Feb]; 49 (4): 583-90 PMID23438854show ga
High-resolution mass spectrometry (MS)-based proteomics has progressed tremendously over the years. For model organisms like yeast, we can now quantify complete proteomes in just a few hours. Developments discussed in this Perspective will soon enable complete proteome analysis of mammalian cells, as well, with profound impact on biology and biomedicine.