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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Afr+Health+Sci 2012 ; 12 (3): 381-7 Nephropedia Template TP
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A study of the intestinal carriage of antibiotic resistant Staphylococcus aureus by Nigerian children #MMPMID23382756
Akinkunmi EO; Lamikanra A
Afr Health Sci 2012[Sep]; 12 (3): 381-7 PMID23382756show ga
BACKGROUND: The gastrointestinal tract has been recognized as a major ecological site for Staphylococcus aureus where it can reach neighboring sites and cause mild or serious infections. OBJECTIVES: To determine the prevalence of intestinal carriage of S. aureus in children aged 3 years and below in Ile-Ife, Nigeria and the antibiotic resistance characteristics of the organisms obtained. METHODS: The organisms isolated in the course of the study were identified by phenotypic and genotypic methods and screened against 13 antibiotics by conventional methods. A total of 293 subjects were sampled of which 130 were diagnosed with diarrheal at the time of the study while the rest were apparently healthy. RESULTS: 14.0% of the faecal samples yielded S. aureus with the carriage rate among the subjects being found to be highest at about 1 month approximately in subjected ages. Sixty-five percent of the isolates were found to be resistant to more than three different antibiotics with more than 50% being resistant to penicillin, erythromycin and trimethoprim. CONCLUSIONS: The results of the study indicated that a reservoir of multiply antibiotic resistant S. aureus exists in the gastrointestinal tracts of children living within the study environment.