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10.3109/02770903.2012.739240 http://scihub22266oqcxt.onion/10.3109/02770903.2012.739240 23134345!ä!23134345 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Asthma 2012 ; 49 (10): 1012-5 Nephropedia Template TP {{tp|p=23134345|t=2012. Magnesium affects the cytokine secretion of CD4(+) T lymphocytes in acute asthma |pdf=|usr=}}{{23134345}} gab.com Text Magnesium affects the cytokine secretion of CD4(+) T lymphocytes in acute asthma JO: J Asthma http://www.kidney.de/pget.php?&tw=1&pmid=23134345 #FOAvip INTRODUCTION: Magnesium (Mg) administration has been shown to promote bronchodilation and to improve lung function in asthma. It also plays an additional role in modulating the immune responses. This study was initiated to explore if Mg supplementation could affect the secretion of cytokines in acute asthmatic CD4(+) T cells. METHODS: Total serum Mg concentrations of the acute asthmatic patients and healthy controls were determined. CD4(+) T cells were isolated from the blood of the acute asthmatic patients. They were cultured in various concentrations of Mg-supplemented (0.8, 5, 10, 15, and 20 mmol/l) medium. Cytokine (IL-5, IL-13, and IFN-gamma) levels were determined by Enzyme-Linked Immunosorbnent Assay (ELISA). RESULTS: Serum Mg concentration was lower in the acute asthmatic patients than that in the healthy controls (p < .05). The secretion of IL-5 and IL-13 was decreased, while the acute asthmatic CD4(+) T cells were cultured in 10 and 15 mmol/l Mg-supplemented medium, respectively, as compared to the 0.8 mmol/l Mg group (p < .05). The secretion of IFN-gamma increased in the 10 mmol/l Mg group (p < .05). CONCLUSION: Mg supplementation was able to modulate the immune responses of acute asthmatic CD4(+) T cells and decrease the secretion of type 2 CD4(+) T lymphocytes cytokines. Twit Text FOAVip Magnesium affects the cytokine secretion of CD4(+) T lymphocytes in acute asthma ????J Asthma http://www.kidney.de/pget.php?&tw=1&pmid=23134345 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23134345 #FOAvip English Wikipedia <ref>{{Cite pmid|23134345}}</ref> Magnesium affects the cytokine secretion of CD4(+) T lymphocytes in acute asthma #MMPMID23134345 Liang RY; Wu W; Huang J; Jiang SP; Lin Y J Asthma 2012[Dec]; 49 (10): 1012-5 PMID23134345show ga INTRODUCTION: Magnesium (Mg) administration has been shown to promote bronchodilation and to improve lung function in asthma. It also plays an additional role in modulating the immune responses. This study was initiated to explore if Mg supplementation could affect the secretion of cytokines in acute asthmatic CD4(+) T cells. METHODS: Total serum Mg concentrations of the acute asthmatic patients and healthy controls were determined. CD4(+) T cells were isolated from the blood of the acute asthmatic patients. They were cultured in various concentrations of Mg-supplemented (0.8, 5, 10, 15, and 20 mmol/l) medium. Cytokine (IL-5, IL-13, and IFN-gamma) levels were determined by Enzyme-Linked Immunosorbnent Assay (ELISA). RESULTS: Serum Mg concentration was lower in the acute asthmatic patients than that in the healthy controls (p < .05). The secretion of IL-5 and IL-13 was decreased, while the acute asthmatic CD4(+) T cells were cultured in 10 and 15 mmol/l Mg-supplemented medium, respectively, as compared to the 0.8 mmol/l Mg group (p < .05). The secretion of IFN-gamma increased in the 10 mmol/l Mg group (p < .05). CONCLUSION: Mg supplementation was able to modulate the immune responses of acute asthmatic CD4(+) T cells and decrease the secretion of type 2 CD4(+) T lymphocytes cytokines. |Acute Disease[MESH] |Adult[MESH] |Asthma/*immunology/metabolism[MESH] |CD4-Positive T-Lymphocytes/*drug effects/*immunology/metabolism[MESH] |Cytokines/*immunology/metabolism[MESH] |Dose-Response Relationship, Drug[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |Female[MESH] |Humans[MESH] |Immune System/drug effects/metabolism[MESH] |Immunologic Factors/administration & dosage/blood/*pharmacology[MESH] |Interferon-gamma/biosynthesis[MESH] |Interleukin-13/biosynthesis[MESH] |Interleukin-5/biosynthesis[MESH] |Magnesium/administration & dosage/blood/*pharmacology[MESH] |Male[MESH] |Middle Aged[MESH] |Th1 Cells/immunology[MESH]Magnesium affects the cytokine secretion of CD4(+) T lymphocytes in ac(epmc).pdf DeepDyve Pubget Overpricing