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10.1089/apc.2012.0216

http://scihub22266oqcxt.onion/10.1089/apc.2012.0216
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suck abstract from ncbi


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pmid23030605      AIDS+Patient+Care+STDS 2012 ; 26 (11): 681-93
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  • A pilot trial of integrated behavioral activation and sexual risk reduction counseling for HIV-uninfected men who have sex with men abusing crystal methamphetamine #MMPMID23030605
  • Mimiaga MJ; Reisner SL; Pantalone DW; O'Cleirigh C; Mayer KH; Safren SA
  • AIDS Patient Care STDS 2012[Nov]; 26 (11): 681-93 PMID23030605show ga
  • Crystal methamphetamine use is a major driver behind high-risk sexual behavior among men who have sex with men (MSM). Prior work suggests a cycle of continued crystal methamphetamine use and high-risk sex due to loss of the ability to enjoy other activities, which appears to be a side effect of this drug. Behavioral activation (BA) is a treatment for depression that involves learning to reengage in life's activities. We evaluated a novel intervention for crystal methamphetamine abuse and high-risk sex in MSM, incorporating 10 sessions of BA with integrated HIV risk reduction counseling (RR). Forty-four subjects were screened, of whom 21 met initial entry criteria. A total of 19 participants enrolled; 16 completed an open-phase study of the intervention. Behavioral assessments were conducted at baseline, 3 months postbaseline, and 6 months postbaseline. Linear mixed effects regression models were fit to assess change over time. Mean unprotected anal intercourse (UAI) episodes decreased significantly from baseline to acute postintervention (beta=-4.86; 95% confidence interval [CI]=-7.48, -2.24; p=0.0015) and from baseline to 6 months postbaseline (beta=-5.07; 95% CI=-7.85, -2.29; p=0.0017; test of fixed effects chi(2)=16.59; df=2,13; p=0.0002). On average, there was a significant decrease over time in the number of crystal methamphetamine episodes in the past 3 months (chi(2)=22.43; df=2,15; p<0.0001), and the number of days of crystal methamphetamine use in the past 30 days (chi(2)=9.21; df=2,15; p=0.010). Statistically significant reductions in depressive symptoms and poly-substance use were also maintained. Adding behavioral activation to risk reduction counseling for MSM with problematic crystal methamphetamine use may augment the potency of a risk reduction intervention for this population. Due to the small sample size and time intensive intervention, future testing in a randomized design is necessary to determine efficacy, with subsequent effectiveness testing.
  • |*Central Nervous System Stimulants[MESH]
  • |*Drug Users[MESH]
  • |*Homosexuality, Male/psychology[MESH]
  • |*Methamphetamine[MESH]
  • |*Risk Reduction Behavior[MESH]
  • |*Sex Counseling[MESH]
  • |*Sexual Partners/psychology[MESH]
  • |Adult[MESH]
  • |Confidence Intervals[MESH]
  • |Depression/epidemiology/*prevention & control/psychology[MESH]
  • |HIV Infections/epidemiology/*prevention & control/psychology[MESH]
  • |Health Knowledge, Attitudes, Practice[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pilot Projects[MESH]
  • |Safe Sex[MESH]


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