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10.1038/cmi.2012.30

http://scihub22266oqcxt.onion/10.1038/cmi.2012.30
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22960604!4002213!22960604
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suck abstract from ncbi

pmid22960604      Cell+Mol+Immunol 2012 ; 9 (6): 439-45
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  • Germinal center kinases in immune regulation #MMPMID22960604
  • Yin H; Shi Z; Jiao S; Chen C; Wang W; Greene MI; Zhou Z
  • Cell Mol Immunol 2012[Nov]; 9 (6): 439-45 PMID22960604show ga
  • Germinal center kinases (GCKs) participate in a variety of signaling pathways needed to regulate cellular functions including apoptosis, cell proliferation, polarity and migration. Recent studies have shown that GCKs are participants in both adaptive and innate immune regulation. However, the differential activation and regulatory mechanisms of GCKs, as well as upstream and downstream signaling molecules, remain to be fully defined. It remains unresolved whether and how GCKs may cross-talk with existing signaling pathways. This review stresses the progresses in research of GCKs relevant to the immune system.
  • |Animals[MESH]
  • |Germinal Center Kinases[MESH]
  • |Humans[MESH]
  • |Immunity/*immunology[MESH]
  • |Inflammation/immunology/pathology[MESH]
  • |Lymphocytes/cytology/enzymology/immunology[MESH]
  • |Models, Immunological[MESH]
  • |Protein Serine-Threonine Kinases/*immunology[MESH]


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