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10.4161/onci.19731

http://scihub22266oqcxt.onion/10.4161/onci.19731
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22934281!3429593!22934281
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suck abstract from ncbi

pmid22934281      Oncoimmunology 2012 ; 1 (5): 780-782
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  • Effect of CpG ODN on monocytic myeloid derived suppressor cells #MMPMID22934281
  • Shirota H; Klinman DM
  • Oncoimmunology 2012[Aug]; 1 (5): 780-782 PMID22934281show ga
  • CpG oligonucleotides stimulate via TLR9 and enhance anti-tumor immunity, an effect attributed to the activation of NK and CD8(+) T cells. Our recent work demonstrates that CpG ODN also induce monocytic myeloid-derived suppressor cells to mature into M1 macrophages, further aiding tumor elimination. This provides insight into the mechanism through which CpG promote tumor regression.
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