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10.1155/2012/749010 http://scihub22266oqcxt.onion/10.1155/2012/749010 22934182!3426247!22934182     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22934182&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Int+J+Nephrol 2012 ; 2012 (?): 749010 Nephropedia Template TP {{tp|p=22934182|t=2012. The glomerular filtration barrier: components and crosstalk |pdf=|usr=}}{{22934182}} gab.com Text The glomerular filtration barrier: components and crosstalk JO: Int J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=22934182 #FOAvip The glomerular filtration barrier is a highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules. Its integrity is maintained by physicochemical and signalling interplay among its three core constituents-the glomerular endothelial cell, the basement membrane and visceral epithelial cell (podocyte). Understanding the pathomechanisms of inherited and acquired human diseases as well as experimental injury models of this barrier have helped to unravel this interdependence. Key among the consequences of interference with the integrity of the glomerular filtration barrier is the appearance of significant amounts of proteins in the urine. Proteinuria correlates with kidney disease progression and cardiovascular mortality. With specific reference to proteinuria in human and animal disease phenotypes, the following review explores the roles of the endothelial cell, glomerular basement membrane, and the podocyte and attempts to highlight examples of essential crosstalk within this barrier. Twit Text FOAVip The glomerular filtration barrier: components and crosstalk ????Int J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=22934182 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22934182 #FOAvip English Wikipedia <ref>{{Cite pmid|22934182}}</ref> The glomerular filtration barrier: components and crosstalk #MMPMID22934182 Menon MC; Chuang PY; He CJ Int J Nephrol 2012[]; 2012 (?): 749010 PMID22934182show ga The glomerular filtration barrier is a highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules. Its integrity is maintained by physicochemical and signalling interplay among its three core constituents-the glomerular endothelial cell, the basement membrane and visceral epithelial cell (podocyte). Understanding the pathomechanisms of inherited and acquired human diseases as well as experimental injury models of this barrier have helped to unravel this interdependence. Key among the consequences of interference with the integrity of the glomerular filtration barrier is the appearance of significant amounts of proteins in the urine. Proteinuria correlates with kidney disease progression and cardiovascular mortality. With specific reference to proteinuria in human and animal disease phenotypes, the following review explores the roles of the endothelial cell, glomerular basement membrane, and the podocyte and attempts to highlight examples of essential crosstalk within this barrier. ?The glomerular filtration barrier: components and crosstalk (epmc).pdf DeepDyve Pubget Overpricing